FKBP3

FKBP3

FK506 binding protein 3, 25kDa, also known as FKBP3, is a human gene.cite web | title = Entrez Gene: FKBP3 FK506 binding protein 3, 25kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2287| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.cite web | title = Entrez Gene: FKBP3 FK506 binding protein 3, 25kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2287| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hung DT, Schreiber SL |title=cDNA cloning of a human 25 kDa FK506 and rapamycin binding protein. |journal=Biochem. Biophys. Res. Commun. |volume=184 |issue= 2 |pages= 733–8 |year= 1992 |pmid= 1374240 |doi=
*cite journal | author=Jin YJ, Burakoff SJ, Bierer BE |title=Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25. |journal=J. Biol. Chem. |volume=267 |issue= 16 |pages= 10942–5 |year= 1992 |pmid= 1375932 |doi=
*cite journal | author=Wiederrecht G, Martin MM, Sigal NH, Siekierka JJ |title=Isolation of a human cDNA encoding a 25 kDa FK-506 and rapamycin binding protein. |journal=Biochem. Biophys. Res. Commun. |volume=185 |issue= 1 |pages= 298–303 |year= 1992 |pmid= 1376117 |doi=
*cite journal | author=Jin YJ, Burakoff SJ |title=The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 16 |pages= 7769–73 |year= 1993 |pmid= 7689229 |doi=
*cite journal | author=Cross SH, Charlton JA, Nan X, Bird AP |title=Purification of CpG islands using a methylated DNA binding column. |journal=Nat. Genet. |volume=6 |issue= 3 |pages= 236–44 |year= 1994 |pmid= 8012384 |doi= 10.1038/ng0394-236
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Yang WM, Yao YL, Seto E |title=The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1. |journal=EMBO J. |volume=20 |issue= 17 |pages= 4814–25 |year= 2001 |pmid= 11532945 |doi= 10.1093/emboj/20.17.4814
*cite journal | author=Meng X, Chen J, Yang Q, "et al." |title=Cloning and identification of a novel cDNA which may be associated with FKBP25. |journal=Biochem. Genet. |volume=40 |issue= 9-10 |pages= 303–10 |year= 2003 |pmid= 12392168 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Won J, Kim M, Yi YW, "et al." |title=A magnetic nanoprobe technology for detecting molecular interactions in live cells. |journal=Science |volume=309 |issue= 5731 |pages= 121–5 |year= 2005 |pmid= 15994554 |doi= 10.1126/science.1112869
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

PBB_Controls
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require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


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