ERP29

Endoplasmic reticulum protein 29 (ERp29) is a human chaperone protein. ERP29 is the human gene encoding it.

Gene

PBB_Summary
section_title =
summary_text = This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.cite web | title = Entrez Gene: ERP29 endoplasmic reticulum protein 29| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10961| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hubbard MJ |title=Functional proteomics: The goalposts are moving. |journal=Proteomics |volume=2 |issue= 9 |pages= 1069–78 |year= 2003 |pmid= 12362325 |doi= 10.1002/1615-9861(200209)2:9<1069::AID-PROT1069>3.0.CO;2-R
*cite journal | author=Mkrtchian S, Sandalova T |title=ERp29, an unusual redox-inactive member of the thioredoxin family. |journal=Antioxid. Redox Signal. |volume=8 |issue= 3-4 |pages= 325–37 |year= 2006 |pmid= 16677078 |doi= 10.1089/ars.2006.8.325
*cite journal | author=Hochstrasser DF, Frutiger S, Paquet N, "et al." |title=Human liver protein
journal=Electrophoresis |volume=13 |issue= 12 |pages= 992–1001 |year= 1993 |pmid= 1286669 |doi=10.1002/elps.11501301201
*cite journal | author=Hughes GJ, Frutiger S, Paquet N, "et al." |title=Human liver protein
journal=Electrophoresis |volume=14 |issue= 11 |pages= 1216–22 |year= 1994 |pmid= 8313870 |doi=10.1002/elps.11501401181
*cite journal | author=Mkrtchian S, Fang C, Hellman U, Ingelman-Sundberg M |title=A stress-inducible rat liver endoplasmic reticulum protein, ERp29. |journal=Eur. J. Biochem. |volume=251 |issue= 1-2 |pages= 304–13 |year= 1998 |pmid= 9492298 |doi=10.1046/j.1432-1327.1998.2510304.x
*cite journal | author=Ferrari DM, Nguyen Van P, Kratzin HD, Söling HD |title=ERp28, a human endoplasmic-reticulum-lumenal protein, is a member of the protein disulfide isomerase family but lacks a CXXC thioredoxin-box motif. |journal=Eur. J. Biochem. |volume=255 |issue= 3 |pages= 570–9 |year= 1998 |pmid= 9738895 |doi=10.1046/j.1432-1327.1998.2550570.x
*cite journal | author=Hubbard MJ, McHugh NJ |title=Human ERp29: isolation, primary structural characterisation and two-dimensional gel mapping. |journal=Electrophoresis |volume=21 |issue= 17 |pages= 3785–96 |year= 2001 |pmid= 11271497 |doi= 10.1002/1522-2683(200011)21:17<3785::AID-ELPS3785>3.0.CO;2-2
*cite journal | author=Shnyder SD, Hubbard MJ |title=ERp29 is a ubiquitous resident of the endoplasmic reticulum with a distinct role in secretory protein production. |journal=J. Histochem. Cytochem. |volume=50 |issue= 4 |pages= 557–66 |year= 2002 |pmid= 11897809 |doi=
*cite journal | author=Sargsyan E, Baryshev M, Backlund M, "et al." |title=Genomic organization and promoter characterization of the gene encoding a putative endoplasmic reticulum chaperone, ERp29. |journal=Gene |volume=285 |issue= 1-2 |pages= 127–39 |year= 2002 |pmid= 12039039 |doi=10.1016/S0378-1119(02)00417-1
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Basrur V, Yang F, Kushimoto T, "et al." |title=Proteomic analysis of early melanosomes: identification of novel melanosomal proteins. |journal=J. Proteome Res. |volume=2 |issue= 1 |pages= 69–79 |year= 2003 |pmid= 12643545 |doi=10.1021/pr025562r
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Cheretis C, Dietrich F, Chatzistamou I, "et al." |title=Expression of ERp29, an endoplasmic reticulum secretion factor in basal-cell carcinoma. |journal=The American Journal of dermatopathology |volume=28 |issue= 5 |pages= 410–2 |year= 2007 |pmid= 17012915 |doi= 10.1097/01.dad.0000211521.49810.ac
*cite journal | author=Zheng J, Liu X, Yan X, "et al." |title=Purification and structural characterization of human ERp29. |journal=Protein Pept. Lett. |volume=13 |issue= 8 |pages= 753–9 |year= 2006 |pmid= 17073718 |doi=10.2174/092986606777841190
*cite journal | author=Chi A, Valencia JC, Hu ZZ, "et al." |title=Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. |journal=J. Proteome Res. |volume=5 |issue= 11 |pages= 3135–44 |year= 2007 |pmid= 17081065 |doi= 10.1021/pr060363j
*cite journal | author=Lippert U, Diao D, Barak NN, Ferrari DM |title=Conserved structural and functional properties of D-domain containing redox-active and -inactive protein disulfide isomerase-related protein chaperones. |journal=J. Biol. Chem. |volume=282 |issue= 15 |pages= 11213–20 |year= 2007 |pmid= 17296603 |doi= 10.1074/jbc.M604440200

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