ECHS1

Enoyl Coenzyme A hydratase, short chain, 1, mitochondrial, also known as ECHS1, is a human gene.cite web | title = Entrez Gene: ECHS1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1892| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.cite web | title = Entrez Gene: ECHS1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1892| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hochstrasser DF, Frutiger S, Paquet N, "et al." |title=Human liver protein
journal=Electrophoresis |volume=13 |issue= 12 |pages= 992–1001 |year= 1993 |pmid= 1286669 |doi=
*cite journal | author=Dawson SJ, White LA |title=Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. |journal=J. Infect. |volume=24 |issue= 3 |pages= 317–20 |year= 1992 |pmid= 1602151 |doi=
*cite journal | author=Li J, Norwood DL, Mao LF, Schulz H |title=Mitochondrial metabolism of valproic acid. |journal=Biochemistry |volume=30 |issue= 2 |pages= 388–94 |year= 1991 |pmid= 1988037 |doi=
*cite journal | author=Jackson S, Schaefer J, Middleton B, Turnbull DM |title=Characterisation of a novel enzyme of human fatty acid beta-oxidation: a matrix-associated, mitochondrial 2-enoyl-CoA hydratase. |journal=Biochem. Biophys. Res. Commun. |volume=214 |issue= 1 |pages= 247–53 |year= 1995 |pmid= 7669045 |doi=
*cite journal | author=Kanazawa M, Ohtake A, Abe H, "et al." |title=Molecular cloning and sequence analysis of the cDNA for human mitochondrial short-chain enoyl-CoA hydratase. |journal=Enzyme Protein |volume=47 |issue= 1 |pages= 9–13 |year= 1994 |pmid= 8012501 |doi=
*cite journal | author=Janssen U, Davis EM, Le Beau MM, Stoffel W |title=Human mitochondrial enoyl-CoA hydratase gene (ECHS1): structural organization and assignment to chromosome 10q26.2-q26.3. |journal=Genomics |volume=40 |issue= 3 |pages= 470–5 |year= 1997 |pmid= 9073515 |doi= 10.1006/geno.1996.4597
*cite journal | author=Hubbard MJ, McHugh NJ |title=Human ERp29: isolation, primary structural characterisation and two-dimensional gel mapping. |journal=Electrophoresis |volume=21 |issue= 17 |pages= 3785–96 |year= 2001 |pmid= 11271497 |doi= 10.1002/1522-2683(200011)21:17<3785::AID-ELPS3785>3.0.CO;2-2 |doilabel=10.1002/1522-2683(200011)21:173785::AID-ELPS37853.0.CO;2-2
*cite journal | author=Jiang LQ, Wen SJ, Wang HY, Chen LY |title=Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system. |journal=Hypertens. Res. |volume=25 |issue= 4 |pages= 647–52 |year= 2003 |pmid= 12358155 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, "et al." |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Bruneel A, Labas V, Mailloux A, "et al." |title=Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis. |journal=Proteomics |volume=5 |issue= 15 |pages= 3876–84 |year= 2006 |pmid= 16130169 |doi= 10.1002/pmic.200401239
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Takahashi M, Watari E, Shinya E, "et al." |title=Suppression of virus replication via down-modulation of mitochondrial short chain enoyl-CoA hydratase in human glioblastoma cells. |journal=Antiviral Res. |volume=75 |issue= 2 |pages= 152–8 |year= 2007 |pmid= 17395278 |doi= 10.1016/j.antiviral.2007.02.002

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