Vesicle-associated membrane protein 8

Vesicle-associated membrane protein 8

Vesicle-associated membrane protein 8 (endobrevin), also known as VAMP8, is a human gene.cite web | title = Entrez Gene: VAMP8 vesicle-associated membrane protein 8 (endobrevin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8673| accessdate = ]

PBB_Summary
section_title =
summary_text = Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. It is associated with the perinuclear vesicular structures of the early endocytic compartment. It has been found that VAMP8 interacts specifically with the soluble NSF-attachment protein (alpha-SNAP), most likely through an VAMP8-containing SNARE complex.cite web | title = Entrez Gene: VAMP8 vesicle-associated membrane protein 8 (endobrevin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8673| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Wong SH, Zhang T, Xu Y, "et al." |title=Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosome. |journal=Mol. Biol. Cell |volume=9 |issue= 6 |pages= 1549–63 |year= 1998 |pmid= 9614193 |doi=
*cite journal | author=Bui TD, Wong SH, Lu L, Hong W |title=Endobrevin maps to chromosome 2 in human and chromosome 6 in mouse. |journal=Genomics |volume=54 |issue= 3 |pages= 579–80 |year= 1999 |pmid= 9878266 |doi= 10.1006/geno.1998.5596
*cite journal | author=Fasshauer D, Antonin W, Margittai M, "et al." |title=Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties. |journal=J. Biol. Chem. |volume=274 |issue= 22 |pages= 15440–6 |year= 1999 |pmid= 10336434 |doi=
*cite journal | author=Kim PK, Hollerbach C, Trimble WS, "et al." |title=Identification of the endoplasmic reticulum targeting signal in vesicle-associated membrane proteins. |journal=J. Biol. Chem. |volume=274 |issue= 52 |pages= 36876–82 |year= 2000 |pmid= 10601239 |doi=
*cite journal | author=Paumet F, Le Mao J, Martin S, "et al." |title=Soluble NSF attachment protein receptors (SNAREs) in RBL-2H3 mast cells: functional role of syntaxin 4 in exocytosis and identification of a vesicle-associated membrane protein 8-containing secretory compartment. |journal=J. Immunol. |volume=164 |issue= 11 |pages= 5850–7 |year= 2000 |pmid= 10820264 |doi=
*cite journal | author=Antonin W, Holroyd C, Tikkanen R, "et al." |title=The R-SNARE endobrevin/VAMP-8 mediates homotypic fusion of early endosomes and late endosomes. |journal=Mol. Biol. Cell |volume=11 |issue= 10 |pages= 3289–98 |year= 2000 |pmid= 11029036 |doi=
*cite journal | author=Antonin W, Holroyd C, Fasshauer D, "et al." |title=A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. |journal=EMBO J. |volume=19 |issue= 23 |pages= 6453–64 |year= 2001 |pmid= 11101518 |doi= 10.1093/emboj/19.23.6453
*cite journal | author=Nagamatsu S, Nakamichi Y, Watanabe T, "et al." |title=Localization of cellubrevin-related peptide, endobrevin, in the early endosome in pancreatic beta cells and its physiological function in exo-endocytosis of secretory granules. |journal=J. Cell. Sci. |volume=114 |issue= Pt 1 |pages= 219–227 |year= 2001 |pmid= 11112705 |doi=
*cite journal | author=Wade N, Bryant NJ, Connolly LM, "et al." |title=Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells. |journal=J. Biol. Chem. |volume=276 |issue= 23 |pages= 19820–7 |year= 2001 |pmid= 11278762 |doi= 10.1074/jbc.M010838200
*cite journal | author=Antonin W, Fasshauer D, Becker S, "et al." |title=Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. |journal=Nat. Struct. Biol. |volume=9 |issue= 2 |pages= 107–11 |year= 2002 |pmid= 11786915 |doi= 10.1038/nsb746
*cite journal | author=Polgár J, Chung SH, Reed GL |title=Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion. |journal=Blood |volume=100 |issue= 3 |pages= 1081–3 |year= 2002 |pmid= 12130530 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Imai A, Nashida T, Yoshie S, Shimomura H |title=Intracellular localisation of SNARE proteins in rat parotid acinar cells: SNARE complexes on the apical plasma membrane. |journal=Arch. Oral Biol. |volume=48 |issue= 8 |pages= 597–604 |year= 2003 |pmid= 12828989 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Brinkman JF, Ottenheim CP, de Jong LA, "et al." |title=VAMP5 and VAMP8 are most likely not involved in primary open-angle glaucoma. |journal=Mol. Vis. |volume=11 |issue= |pages= 582–6 |year= 2006 |pmid= 16110299 |doi=
*cite journal | author=Oishi Y, Arakawa T, Tanimura A, "et al." |title=Role of VAMP-2, VAMP-7, and VAMP-8 in constitutive exocytosis from HSY cells. |journal=Histochem. Cell Biol. |volume=125 |issue= 3 |pages= 273–81 |year= 2007 |pmid= 16195891 |doi= 10.1007/s00418-005-0068-y
*cite journal | author=Shiffman D, Rowland CM, Louie JZ, "et al." |title=Gene variants of VAMP8 and HNRPUL1 are associated with early-onset myocardial infarction. |journal=Arterioscler. Thromb. Vasc. Biol. |volume=26 |issue= 7 |pages= 1613–8 |year= 2006 |pmid= 16690874 |doi= 10.1161/01.ATV.0000226543.77214.e4

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Vesicle-associated membrane protein — (VAMP) family of proteins includes proteins with similar structure. * VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neuromediator release. * VAMP3… …   Wikipedia

  • SNARE (protein) — Molecular machinery driving vesicle fusion in neuromediator release. The core SNARE complex is formed by four α helices contributed by synaptobrevin, syntaxin and SNAP 25, synaptotagmin serves as a calcium sensor and regulates intimately the… …   Wikipedia

  • Synaptic vesicle — Neuron A (transmitting) to neuron B (receiving) 1. Mitochondria 2. synaptic vesicle with neurotransmitters 3. Autoreceptor 4. Synapse with neurotransmitter released (serotonin) 5. Postsynaptic receptors activated by neurotransmitter (induction of …   Wikipedia

  • Vesicle (biology and chemistry) — Scheme of a simple vesicle (liposome). A vesicle is a bubble of liquid within another liquid, a supramolecular assembly made up of many different molecules. More technically, a vesicle is a small membrane enclosed sack that can store or transport …   Wikipedia

  • Vesicle (biology) — A vesicle is a small bubble of liquid within a cell. A more formal definition in cell biology, would be that a vesicle is a relatively small, intracellular, membrane enclosed sac that stores or transports substances. Vesicles form naturally… …   Wikipedia

  • Vesicle — In dermatology, a vesicle is a small blister, as on the skin. Vesicles also occur on the mucous membranes, such as the buccal mucosa (the lining of the mouth). Vesicles are less than .5 centimeters in diameter.In anatomy, a vesicle is any small… …   Medical dictionary

  • Cell membrane — Illustration of a Eukaryotic cell membrane The cell membrane or plasma membrane is a biological mem …   Wikipedia

  • G protein-coupled receptor — G protein coupled receptors (GPCRs), also known as seven transmembrane domain receptors, 7TM receptors, heptahelical receptors, and G protein linked receptors (GPLR), comprise a large protein family of transmembrane receptors that sense molecules …   Wikipedia

  • VAMP2 — Vesicle associated membrane protein 2 (synaptobrevin 2), also known as VAMP2, is a human gene.cite web | title = Entrez Gene: VAMP2 vesicle associated membrane protein 2 (synaptobrevin 2)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • VAMP3 — Vesicle associated membrane protein 3 (cellubrevin), also known as VAMP3, is a human gene.cite web | title = Entrez Gene: VAMP3 vesicle associated membrane protein 3 (cellubrevin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”