- UXT
Ubiquitously-expressed transcript, also known as UXT, is a human
gene .cite web | title = Entrez Gene: UXT ubiquitously-expressed transcript| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8409| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a novel protein which is highly conserved in mouse. It interacts with the N-terminus of the androgen receptor and plays a role in facilitating receptor-induced transcriptional activation. It is also likely to be involved in tumorigenesis as it is abundantly expressed in tumor tissues. This gene is part of a gene cluster on chromosome Xp11.23. Alternative splicing results in 2 transcript variants encoding different isoforms.cite web | title = Entrez Gene: UXT ubiquitously-expressed transcript| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8409| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Schroer A, Schneider S, Ropers H, Nothwang H |title=Cloning and characterization of UXT, a novel gene in human Xp11, which is widely and abundantly expressed in tumor tissue. |journal=Genomics |volume=56 |issue= 3 |pages= 340–3 |year= 1999 |pmid= 10087202 |doi=
*cite journal | author=Zhang QH, Ye M, Wu XY, "et al." |title=Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. |journal=Genome Res. |volume=10 |issue= 10 |pages= 1546–60 |year= 2001 |pmid= 11042152 |doi=
*cite journal | author=Weinmann AS, Yan PS, Oberley MJ, "et al." |title=Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. |journal=Genes Dev. |volume=16 |issue= 2 |pages= 235–44 |year= 2002 |pmid= 11799066 |doi= 10.1101/gad.943102
*cite journal | author=Liu L, McKeehan WL |title=Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity. |journal=Genomics |volume=79 |issue= 1 |pages= 124–36 |year= 2002 |pmid= 11827465 |doi= 10.1006/geno.2001.6679
*cite journal | author=Markus SM, Taneja SS, Logan SK, "et al." |title=Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus. |journal=Mol. Biol. Cell |volume=13 |issue= 2 |pages= 670–82 |year= 2002 |pmid= 11854421 |doi= 10.1091/mbc.01-10-0513
*cite journal | author=Thiselton DL, McDowall J, Brandau O, "et al." |title=An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders. |journal=Genomics |volume=79 |issue= 4 |pages= 560–72 |year= 2002 |pmid= 11944989 |doi= 10.1006/geno.2002.6733
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Liu L, Amy V, Liu G, McKeehan WL |title=Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells. |journal=In Vitro Cell. Dev. Biol. Anim. |volume=38 |issue= 10 |pages= 582–94 |year= 2003 |pmid= 12762840 |doi=
*cite journal | author=Gstaiger M, Luke B, Hess D, "et al." |title=Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI. |journal=Science |volume=302 |issue= 5648 |pages= 1208–12 |year= 2003 |pmid= 14615539 |doi= 10.1126/science.1088401
*cite journal | author=Rayala HJ, Kendirgi F, Barry DM, "et al." |title=The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155. |journal=Mol. Cell Proteomics |volume=3 |issue= 2 |pages= 145–55 |year= 2004 |pmid= 14645504 |doi= 10.1074/mcp.M300106-MCP200
*cite journal | author=Taneja SS, Ha S, Swenson NK, "et al." |title=ART-27, an androgen receptor coactivator regulated in prostate development and cancer. |journal=J. Biol. Chem. |volume=279 |issue= 14 |pages= 13944–52 |year= 2004 |pmid= 14711828 |doi= 10.1074/jbc.M306576200
*cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ross MT, Grafham DV, Coffey AJ, "et al." |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Zhao H, Wang Q, Zhang H, "et al." |title=UXT is a novel centrosomal protein essential for cell viability. |journal=Mol. Biol. Cell |volume=16 |issue= 12 |pages= 5857–65 |year= 2006 |pmid= 16221885 |doi= 10.1091/mbc.E05-08-0705
*cite journal | author=Moss TN, Vo A, McKeehan WL, Liu L |title=UXT (Ubiquitously Expressed Transcript) causes mitochondrial aggregation. |journal=In Vitro Cell. Dev. Biol. Anim. |volume=43 |issue= 3-4 |pages= 139–46 |year= 2007 |pmid= 17554592 |doi= 10.1007/s11626-007-9016-6
*cite journal | author=Sun S, Tang Y, Lou X, "et al." |title=UXT is a novel and essential cofactor in the NF-kappaB transcriptional enhanceosome. |journal=J. Cell Biol. |volume=178 |issue= 2 |pages= 231–44 |year= 2007 |pmid= 17620405 |doi= 10.1083/jcb.200611081PBB_Controls
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