[cite web | title = Entrez Gene: RRM2B ribonucleotide reductase M2 B (TP53 inducible)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50484| accessdate = ] ] PBB_Summary
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References
Further reading
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citations =
*cite journal | author=Tanaka H, Arakawa H, Yamaguchi T, "et al." |title=A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. |journal=Nature |volume=404 |issue= 6773 |pages= 42–9 |year= 2000 |pmid= 10716435 |doi= 10.1038/35003506
*cite journal | author=Nakano K, Bálint E, Ashcroft M, Vousden KH |title=A ribonucleotide reductase gene is a transcriptional target of p53 and p73. |journal=Oncogene |volume=19 |issue= 37 |pages= 4283–9 |year= 2000 |pmid= 10980602 |doi=
*cite journal | author=Guittet O, Håkansson P, Voevodskaya N, "et al." |title=Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells. |journal=J. Biol. Chem. |volume=276 |issue= 44 |pages= 40647–51 |year= 2001 |pmid= 11517226 |doi= 10.1074/jbc.M106088200
*cite journal | author=Yamaguchi T, Matsuda K, Sagiya Y, "et al." |title=p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint. |journal=Cancer Res. |volume=61 |issue= 22 |pages= 8256–62 |year= 2001 |pmid= 11719458 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Yanamoto S, Kawasaki G, Yoshitomi I, Mizuno A |title=Expression of p53R2, newly p53 target in oral normal epithelium, epithelial dysplasia and squamous cell carcinoma. |journal=Cancer Lett. |volume=190 |issue= 2 |pages= 233–43 |year= 2003 |pmid= 12565178 |doi=
*cite journal | author=Xue L, Zhou B, Liu X, "et al." |title=Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits. |journal=Cancer Res. |volume=63 |issue= 5 |pages= 980–6 |year= 2003 |pmid= 12615712 |doi=
*cite journal | author=Zhou B, Liu X, Mo X, "et al." |title=The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53. |journal=Cancer Res. |volume=63 |issue= 20 |pages= 6583–94 |year= 2003 |pmid= 14583450 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Shao J, Zhou B, Zhu L, "et al." |title=In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase. |journal=Cancer Res. |volume=64 |issue= 1 |pages= 1–6 |year= 2004 |pmid= 14729598 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ceballos E, Muñoz-Alonso MJ, Berwanger B, "et al." |title=Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes. |journal=Oncogene |volume=24 |issue= 28 |pages= 4559–71 |year= 2005 |pmid= 15856024 |doi= 10.1038/sj.onc.1208652
*cite journal | author=Deng ZL, Xie DW, Bostick RM, "et al." |title=Novel genetic variations of the p53R2 gene in patients with colorectal adenoma and controls. |journal=World J. Gastroenterol. |volume=11 |issue= 33 |pages= 5169–73 |year= 2005 |pmid= 16127747 |doi=
*cite journal | author=Ohno K, Tanaka-Azuma Y, Yoneda Y, Yamada T |title=Genotoxicity test system based on p53R2 gene expression in human cells: examination with 80 chemicals. |journal=Mutat. Res. |volume=588 |issue= 1 |pages= 47–57 |year= 2006 |pmid= 16236544 |doi= 10.1016/j.mrgentox.2005.09.002
*cite journal | author=Qiu W, Zhou B, Darwish D, "et al." |title=Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits. |journal=Biochem. Biophys. Res. Commun. |volume=340 |issue= 2 |pages= 428–34 |year= 2006 |pmid= 16376858 |doi= 10.1016/j.bbrc.2005.12.019
*cite journal | author=Okumura H, Natsugoe S, Yokomakura N, "et al." |title=Expression of p53R2 is related to prognosis in patients with esophageal squamous cell carcinoma. |journal=Clin. Cancer Res. |volume=12 |issue= 12 |pages= 3740–5 |year= 2006 |pmid= 16778101 |doi= 10.1158/1078-0432.CCR-05-2416
*cite journal | author=Yen Y, Chu B, Yen C, "et al." |title=Enzymatic property analysis of p53R2 subunit of human ribonucleotide reductase. |journal=Adv. Enzyme Regul. |volume=46 |issue= |pages= 235–47 |year= 2007 |pmid= 16846634 |doi= 10.1016/j.advenzreg.2006.01.016
*cite journal | author=Lembo D, Donalisio M, Cornaglia M, "et al." |title=Effect of high-risk human papillomavirus oncoproteins on p53R2 gene expression after DNA damage. |journal=Virus Res. |volume=122 |issue= 1-2 |pages= 189–93 |year= 2007 |pmid= 16872707 |doi= 10.1016/j.virusres.2006.06.011
*cite journal | author=Bourdon A, Minai L, Serre V, "et al." |title=Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion. |journal=Nat. Genet. |volume=39 |issue= 6 |pages= 776–80 |year= 2007 |pmid= 17486094 |doi= 10.1038/ng2040
*cite journal | author=Yokomakura N, Natsugoe S, Okumura H, "et al." |title=Improvement in radiosensitivity using small interfering RNA targeting p53R2 in esophageal squamous cell carcinoma. |journal=Oncol. Rep. |volume=18 |issue= 3 |pages= 561–7 |year= 2007 |pmid= 17671702 |doi=
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