PRPF6

PRPF6

PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae), also known as PRPF6, is a human gene.cite web | title = Entrez Gene: PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=24148| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.cite web | title = Entrez Gene: PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=24148| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Nishikimi A, Mukai J, Kioka N, Yamada M |title=A novel mammalian nuclear protein similar to Schizosaccharomyces pombe Prp1p/Zer1p and Saccharomyces cerevisiae Prp6p pre-mRNA splicing factors. |journal=Biochim. Biophys. Acta |volume=1435 |issue= 1-2 |pages= 147–52 |year= 2000 |pmid= 10561546 |doi=
*cite journal | author=Makarov EM, Makarova OV, Achsel T, Lührmann R |title=The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. |journal=J. Mol. Biol. |volume=298 |issue= 4 |pages= 567–75 |year= 2000 |pmid= 10788320 |doi= 10.1006/jmbi.2000.3685
*cite journal | author=Yuryev A, Ono M, Goff SA, "et al." |title=Isoform-specific localization of A-RAF in mitochondria. |journal=Mol. Cell. Biol. |volume=20 |issue= 13 |pages= 4870–8 |year= 2000 |pmid= 10848612 |doi=
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Jurica MS, Licklider LJ, Gygi SR, "et al." |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=
*cite journal | author=Zhao Y, Goto K, Saitoh M, "et al." |title=Activation function-1 domain of androgen receptor contributes to the interaction between subnuclear splicing factor compartment and nuclear receptor compartment. Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a coactivator for the receptor. |journal=J. Biol. Chem. |volume=277 |issue= 33 |pages= 30031–9 |year= 2002 |pmid= 12039962 |doi= 10.1074/jbc.M203811200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Yuryev A, Wennogle LP |title=Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis. |journal=Genomics |volume=81 |issue= 2 |pages= 112–25 |year= 2003 |pmid= 12620389 |doi=
*cite journal | author=Goto K, Zhao Y, Saito M, "et al." |title=Activation function-1 domain of androgen receptor contributes to the interaction between two distinct subnuclear compartments. |journal=J. Steroid Biochem. Mol. Biol. |volume=85 |issue= 2-5 |pages= 201–8 |year= 2003 |pmid= 12943705 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Will CL, Schneider C, Hossbach M, "et al." |title=The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. |journal=RNA |volume=10 |issue= 6 |pages= 929–41 |year= 2004 |pmid= 15146077 |doi=
*cite journal | author=Sun X, Zhang H, Wang D, "et al." |title=DLP, a novel Dim1 family protein implicated in pre-mRNA splicing and cell cycle progression. |journal=J. Biol. Chem. |volume=279 |issue= 31 |pages= 32839–47 |year= 2004 |pmid= 15161931 |doi= 10.1074/jbc.M402522200
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Laggerbauer B, Liu S, Makarov E, "et al." |title=The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation. |journal=RNA |volume=11 |issue= 5 |pages= 598–608 |year= 2005 |pmid= 15840814 |doi= 10.1261/rna.2300805
*cite journal | author=Batsché E, Yaniv M, Muchardt C |title=The human SWI/SNF subunit Brm is a regulator of alternative splicing. |journal=Nat. Struct. Mol. Biol. |volume=13 |issue= 1 |pages= 22–9 |year= 2006 |pmid= 16341228 |doi= 10.1038/nsmb1030
*cite journal | author=Fan S, Goto K, Chen G, "et al." |title=Identification of the functional domains of ANT-1, a novel coactivator of the androgen receptor. |journal=Biochem. Biophys. Res. Commun. |volume=341 |issue= 1 |pages= 192–201 |year= 2006 |pmid= 16414017 |doi= 10.1016/j.bbrc.2005.12.167
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • PRPF6 — PRP6 pre mRNA processing factor 6 homolog (S. cerevisiae) HUGO 15860 Símbolo PRPF6 Símbolos alt. ANT 1; C20orf14; T …   Wikipedia Español

  • RNA splicing — In molecular biology and genetics, splicing is a modification of an RNA after transcription, in which introns are removed and exons are joined. This is needed for the typical eukaryotic messenger RNA before it can be used to produce a correct… …   Wikipedia

  • Alternative splicing — produces two protein isoforms. Alternative splicing (or differential splicing) is a process by which the exons of the RNA produced by transcription of a gene (a primary gene transcript or pre mRNA) are reconnected in multiple ways during RNA… …   Wikipedia

  • Polyadenylation — Typical structure of a mature eukaryotic mRNA Polyadenylation is the addition of a poly(A) tail to an RNA molecule. The poly(A) tail consists of multiple adenosine monophosphates; in other words, it is a stretch of RNA that has only adenine bases …   Wikipedia

  • Androgen receptor — Structure of the ligand binding domain of the androgen receptor (rainbow cartoon) complexed with testosterone (white sticks).[1] …   Wikipedia

  • Cleavage and polyadenylation specificity factor — (CPSF) (or Cleavage polyadenylation stimulating factor) is involved in the cleavage of the 3 signaling region from a newly synthesized pre messenger RNA (pre mRNA) molecule in the process of gene transcription. It is the first protein to bind to… …   Wikipedia

  • Cleavage stimulation factor — Cleavage stimulatory factor or cleavage stimulation factor (CstF or CStF) is a heterotrimeric protein of about 200 kilodaltons that is involved in the cleavage of the 3 signaling region from a newly synthesized pre messenger RNA (mRNA) molecule.… …   Wikipedia

  • PABPN1 — Poly(A) binding protein, nuclear 1 Rendering based on PDB 3B4D …   Wikipedia

  • DCP2 — decapping enzyme homolog (S. cerevisiae) Identifiers Symbols DCP2; FLJ33245; NUDT20 External IDs …   Wikipedia

  • DCP1A — DCP1 decapping enzyme homolog A (S. cerevisiae) Identifiers Symbols DCP1A; FLJ21691; HSA275986; Nbla00360; SMAD4IP1; SMIF External IDs …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”