PRPF6

PRPF6

PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae), also known as PRPF6, is a human gene.cite web | title = Entrez Gene: PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=24148| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.cite web | title = Entrez Gene: PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=24148| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Nishikimi A, Mukai J, Kioka N, Yamada M |title=A novel mammalian nuclear protein similar to Schizosaccharomyces pombe Prp1p/Zer1p and Saccharomyces cerevisiae Prp6p pre-mRNA splicing factors. |journal=Biochim. Biophys. Acta |volume=1435 |issue= 1-2 |pages= 147–52 |year= 2000 |pmid= 10561546 |doi=
*cite journal | author=Makarov EM, Makarova OV, Achsel T, Lührmann R |title=The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. |journal=J. Mol. Biol. |volume=298 |issue= 4 |pages= 567–75 |year= 2000 |pmid= 10788320 |doi= 10.1006/jmbi.2000.3685
*cite journal | author=Yuryev A, Ono M, Goff SA, "et al." |title=Isoform-specific localization of A-RAF in mitochondria. |journal=Mol. Cell. Biol. |volume=20 |issue= 13 |pages= 4870–8 |year= 2000 |pmid= 10848612 |doi=
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Jurica MS, Licklider LJ, Gygi SR, "et al." |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=
*cite journal | author=Zhao Y, Goto K, Saitoh M, "et al." |title=Activation function-1 domain of androgen receptor contributes to the interaction between subnuclear splicing factor compartment and nuclear receptor compartment. Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a coactivator for the receptor. |journal=J. Biol. Chem. |volume=277 |issue= 33 |pages= 30031–9 |year= 2002 |pmid= 12039962 |doi= 10.1074/jbc.M203811200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Yuryev A, Wennogle LP |title=Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis. |journal=Genomics |volume=81 |issue= 2 |pages= 112–25 |year= 2003 |pmid= 12620389 |doi=
*cite journal | author=Goto K, Zhao Y, Saito M, "et al." |title=Activation function-1 domain of androgen receptor contributes to the interaction between two distinct subnuclear compartments. |journal=J. Steroid Biochem. Mol. Biol. |volume=85 |issue= 2-5 |pages= 201–8 |year= 2003 |pmid= 12943705 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Will CL, Schneider C, Hossbach M, "et al." |title=The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. |journal=RNA |volume=10 |issue= 6 |pages= 929–41 |year= 2004 |pmid= 15146077 |doi=
*cite journal | author=Sun X, Zhang H, Wang D, "et al." |title=DLP, a novel Dim1 family protein implicated in pre-mRNA splicing and cell cycle progression. |journal=J. Biol. Chem. |volume=279 |issue= 31 |pages= 32839–47 |year= 2004 |pmid= 15161931 |doi= 10.1074/jbc.M402522200
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Laggerbauer B, Liu S, Makarov E, "et al." |title=The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation. |journal=RNA |volume=11 |issue= 5 |pages= 598–608 |year= 2005 |pmid= 15840814 |doi= 10.1261/rna.2300805
*cite journal | author=Batsché E, Yaniv M, Muchardt C |title=The human SWI/SNF subunit Brm is a regulator of alternative splicing. |journal=Nat. Struct. Mol. Biol. |volume=13 |issue= 1 |pages= 22–9 |year= 2006 |pmid= 16341228 |doi= 10.1038/nsmb1030
*cite journal | author=Fan S, Goto K, Chen G, "et al." |title=Identification of the functional domains of ANT-1, a novel coactivator of the androgen receptor. |journal=Biochem. Biophys. Res. Commun. |volume=341 |issue= 1 |pages= 192–201 |year= 2006 |pmid= 16414017 |doi= 10.1016/j.bbrc.2005.12.167
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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