RANBP1

RAN binding protein 1, also known as RANBP1, is a human gene.cite web | title = Entrez Gene: RANBP1 RAN binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5902| accessdate = ]

PBB_Summary
section_title =
summary_text = Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.cite web | title = Entrez Gene: RANBP1 RAN binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5902| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hayashi N, Yokoyama N, Seki T, "et al." |title=RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4. |journal=Mol. Gen. Genet. |volume=247 |issue= 6 |pages= 661–9 |year= 1995 |pmid= 7616957 |doi=
*cite journal | author=Bischoff FR, Krebber H, Smirnova E, "et al." |title=Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1. |journal=EMBO J. |volume=14 |issue= 4 |pages= 705–15 |year= 1995 |pmid= 7882974 |doi=
*cite journal | author=Ren M, Villamarin A, Shih A, "et al." |title=Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing. |journal=Mol. Cell. Biol. |volume=15 |issue= 4 |pages= 2117–24 |year= 1995 |pmid= 7891706 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Coutavas E, Ren M, Oppenheim JD, "et al." |title=Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4. |journal=Nature |volume=366 |issue= 6455 |pages= 585–7 |year= 1994 |pmid= 8255297 |doi= 10.1038/366585a0
*cite journal | author=Zolotukhin AS, Felber BK |title=Mutations in the nuclear export signal of human ran-binding protein RanBP1 block the Rev-mediated posttranscriptional regulation of human immunodeficiency virus type 1. |journal=J. Biol. Chem. |volume=272 |issue= 17 |pages= 11356–60 |year= 1997 |pmid= 9111043 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Kehlenbach RH, Dickmanns A, Kehlenbach A, "et al." |title=A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export. |journal=J. Cell Biol. |volume=145 |issue= 4 |pages= 645–57 |year= 1999 |pmid= 10330396 |doi=
*cite journal | author=Plafker K, Macara IG |title=Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1. |journal=Mol. Cell. Biol. |volume=20 |issue= 10 |pages= 3510–21 |year= 2000 |pmid= 10779340 |doi=
*cite journal | author=Steggerda SM, Paschal BM |title=The mammalian Mog1 protein is a guanine nucleotide release factor for Ran. |journal=J. Biol. Chem. |volume=275 |issue= 30 |pages= 23175–80 |year= 2000 |pmid= 10811801 |doi= 10.1074/jbc.C000252200
*cite journal | author=Maynard TM, Haskell GT, Bhasin N, "et al." |title=RanBP1, a velocardiofacial/DiGeorge syndrome candidate gene, is expressed at sites of mesenchymal/epithelial induction. |journal=Mech. Dev. |volume=111 |issue= 1-2 |pages= 177–80 |year= 2002 |pmid= 11804793 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Di Fiore B, Ciciarello M, Mangiacasale R, "et al." |title=Mammalian RanBP1 regulates centrosome cohesion during mitosis. |journal=J. Cell. Sci. |volume=116 |issue= Pt 16 |pages= 3399–411 |year= 2004 |pmid= 12840069 |doi= 10.1242/jcs.00624
*cite journal | author=Seewald MJ, Kraemer A, Farkasovsky M, "et al." |title=Biochemical characterization of the Ran-RanBP1-RanGAP system: are RanBP proteins and the acidic tail of RanGAP required for the Ran-RanGAP GTPase reaction? |journal=Mol. Cell. Biol. |volume=23 |issue= 22 |pages= 8124–36 |year= 2003 |pmid= 14585972 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Bohlson SS, Zhang M, Ortiz CE, Tenner AJ |title=CD93 interacts with the PDZ domain-containing adaptor protein GIPC: implications in the modulation of phagocytosis. |journal=J. Leukoc. Biol. |volume=77 |issue= 1 |pages= 80–9 |year= 2005 |pmid= 15459234 |doi= 10.1189/jlb.0504305
*cite journal | author=Collins JE, Wright CL, Edwards CA, "et al." |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84
*cite journal | author=Bruneel A, Labas V, Mailloux A, "et al." |title=Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis. |journal=Proteomics |volume=5 |issue= 15 |pages= 3876–84 |year= 2006 |pmid= 16130169 |doi= 10.1002/pmic.200401239
*cite journal | author=Takeda E, Hieda M, Katahira J, Yoneda Y |title=Phosphorylation of RanGAP1 stabilizes its interaction with Ran and RanBP1. |journal=Cell Struct. Funct. |volume=30 |issue= 2 |pages= 69–80 |year= 2006 |pmid= 16428860 |doi=
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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