- FUT7
Fucosyltransferase 7 (alpha (1,3) fucosyltransferase), also known as FUT7, is a human
gene .cite web | title = Entrez Gene: FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2529| accessdate = ]PBB_Summary
section_title =
summary_text = The sialyl Lewis x oligosaccharide determinant is an essential component of leukocyte counterreceptors for E-selectin- (MIM 131210) and P-selectin- (MIM 173610) mediated adhesions of leukocytes. This oligosaccharide molecule is displayed on the surfaces of granulocytes, monocytes, and natural killer cells. Formation of leukocyte adhesions to these selectins is an early and important step in the process that ultimately allows leukocytes to leave the vascular tree and become recruited into lymphoid tissues and sites of inflammation. [supplied by OMIM] cite web | title = Entrez Gene: FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2529| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Natsuka S, Gersten KM, Zenita K, "et al." |title=Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant. |journal=J. Biol. Chem. |volume=269 |issue= 32 |pages= 20806 |year= 1994 |pmid= 8051184 |doi=
*cite journal | author=Sasaki K, Kurata K, Funayama K, "et al." |title=Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes. |journal=J. Biol. Chem. |volume=269 |issue= 20 |pages= 14730–7 |year= 1994 |pmid= 8182079 |doi=
*cite journal | author=Natsuka S, Gersten KM, Zenita K, "et al." |title=Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant. |journal=J. Biol. Chem. |volume=269 |issue= 24 |pages= 16789–94 |year= 1994 |pmid= 8207002 |doi=
*cite journal | author=Smith PL, Gersten KM, Petryniak B, "et al." |title=Expression of the alpha(1,3)fucosyltransferase Fuc-TVII in lymphoid aggregate high endothelial venules correlates with expression of L-selectin ligands. |journal=J. Biol. Chem. |volume=271 |issue= 14 |pages= 8250–9 |year= 1996 |pmid= 8626519 |doi=
*cite journal | author=Le Marer N, Palcic MM, Clarke JL, "et al." |title=Developmental regulation of alpha 1,3-fucosyltransferase expression in CD34 positive progenitors and maturing myeloid cells isolated from normal human bone marrow. |journal=Glycobiology |volume=7 |issue= 3 |pages= 357–65 |year= 1997 |pmid= 9147044 |doi=
*cite journal | author=Mas E, Pasqualini E, Caillol N, "et al." |title=Fucosyltransferase activities in human pancreatic tissue: comparative study between cancer tissues and established tumoral cell lines. |journal=Glycobiology |volume=8 |issue= 6 |pages= 605–13 |year= 1998 |pmid= 9592127 |doi=
*cite journal | author=Bengtson P, Larson C, Lundblad A, "et al." |title=Identification of a missense mutation (G329A;Arg(110)--> GLN) in the human FUT7 gene. |journal=J. Biol. Chem. |volume=276 |issue= 34 |pages= 31575–82 |year= 2001 |pmid= 11404359 |doi= 10.1074/jbc.M104165200
*cite journal | author=de Vries T, Yen TY, Joshi RK, "et al." |title=Neighboring cysteine residues in human fucosyltransferase VII are engaged in disulfide bridges, forming small loop structures. |journal=Glycobiology |volume=11 |issue= 5 |pages= 423–32 |year= 2001 |pmid= 11425803 |doi=
*cite journal | author=Roos C, Kolmer M, Mattila P, Renkonen R |title=Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism. |journal=J. Biol. Chem. |volume=277 |issue= 5 |pages= 3168–75 |year= 2002 |pmid= 11698403 |doi= 10.1074/jbc.M107927200
*cite journal | author=Zerfaoui M, Fukuda M, Langlet C, "et al." |title=The cytosolic and transmembrane domains of the beta 1,6 N-acetylglucosaminyltransferase (C2GnT) function as a cis to medial/Golgi-targeting determinant. |journal=Glycobiology |volume=12 |issue= 1 |pages= 15–24 |year= 2002 |pmid= 11825883 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Hiraiwa N, Yabuta T, Yoritomi K, "et al." |title=Transactivation of the fucosyltransferase VII gene by human T-cell leukemia virus type 1 Tax through a variant cAMP-responsive element. |journal=Blood |volume=101 |issue= 9 |pages= 3615–21 |year= 2003 |pmid= 12506041 |doi= 10.1182/blood-2002-07-2301
*cite journal | author=Humphray SJ, Oliver K, Hunt AR, "et al." |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465
*cite journal | author=Zisoulis DG, Kansas GS |title=H-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cells. |journal=J. Biol. Chem. |volume=279 |issue= 38 |pages= 39495–504 |year= 2004 |pmid= 15262995 |doi= 10.1074/jbc.M407904200
*cite journal | author=Miyashiro M, Furuya S, Fujishige K, Sugita T |title=Highly sensitive cell-based assay system to monitor the sialyl Lewis X biosynthesis mediated by alpha1-3 fucosyltransferase-VII. |journal=Biochem. Biophys. Res. Commun. |volume=324 |issue= 1 |pages= 98–107 |year= 2004 |pmid= 15464988 |doi= 10.1016/j.bbrc.2004.09.025
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Martinez M, Joffraud M, Giraud S, "et al." |title=Regulation of PSGL-1 interactions with L-selectin, P-selectin, and E-selectin: role of human fucosyltransferase-IV and -VII. |journal=J. Biol. Chem. |volume=280 |issue= 7 |pages= 5378–90 |year= 2005 |pmid= 15579466 |doi= 10.1074/jbc.M410899200
*cite journal | author=Prorok-Hamon M, Notel F, Mathieu S, "et al." |title=N-glycans of core2 beta(1,6)-N-acetylglucosaminyltransferase-I (C2GnT-I) but not those of alpha(1,3)-fucosyltransferase-VII (FucT-VII) are required for the synthesis of functional P-selectin glycoprotein ligand-1 (PSGL-1): effects on P-, L- and E-selectin binding. |journal=Biochem. J. |volume=391 |issue= Pt 3 |pages= 491–502 |year= 2006 |pmid= 15926890 |doi= 10.1042/BJ20050344
*cite journal | author=Brown V, Brown RA, Ozinsky A, "et al." |title=Binding specificity of Toll-like receptor cytoplasmic domains. |journal=Eur. J. Immunol. |volume=36 |issue= 3 |pages= 742–53 |year= 2006 |pmid= 16482509 |doi= 10.1002/eji.200535158
*cite journal | author=Wang QY, Zhang Y, Chen HJ, "et al." |title=Alpha 1,3-fucosyltransferase-VII regulates the signaling molecules of the insulin receptor pathway. |journal=FEBS J. |volume=274 |issue= 2 |pages= 526–38 |year= 2007 |pmid= 17229154 |doi= 10.1111/j.1742-4658.2006.05599.xPBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
Wikimedia Foundation. 2010.
