- MAP1LC3B
Microtubule-associated protein 1 light chain 3 beta, also known as MAP1LC3B, is a human
gene .cite web | title = Entrez Gene: MAP1LC3B microtubule-associated protein 1 light chain 3 beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81631| accessdate = ]PBB_Summary
section_title =
summary_text = The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.cite web | title = Entrez Gene: MAP1LC3B microtubule-associated protein 1 light chain 3 beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81631| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Snásel J, Pichová I |title=The cleavage of host cell proteins by HIV-1 protease. |journal=Folia Biol. (Praha) |volume=42 |issue= 5 |pages= 227–30 |year= 1997 |pmid= 8997639 |doi=
*cite journal | author=Tanida I, Ueno T, Kominami E |title=LC3 conjugation system in mammalian autophagy. |journal=Int. J. Biochem. Cell Biol. |volume=36 |issue= 12 |pages= 2503–18 |year= 2005 |pmid= 15325588 |doi= 10.1016/j.biocel.2004.05.009
*cite journal | author=Wallin M, Deinum J, Goobar L, Danielson UH |title=Proteolytic cleavage of microtubule-associated proteins by retroviral proteinases. |journal=J. Gen. Virol. |volume=71 ( Pt 9) |issue= |pages= 1985–91 |year= 1990 |pmid= 2212989 |doi=
*cite journal | author=Kabeya Y, Mizushima N, Ueno T, "et al." |title=LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. |journal=EMBO J. |volume=19 |issue= 21 |pages= 5720–8 |year= 2000 |pmid= 11060023 |doi= 10.1093/emboj/19.21.5720
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=Tanida I, Tanida-Miyake E, Komatsu M, "et al." |title=Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p. |journal=J. Biol. Chem. |volume=277 |issue= 16 |pages= 13739–44 |year= 2002 |pmid= 11825910 |doi= 10.1074/jbc.M200385200
*cite journal | author=Tanida I, Tanida-Miyake E, Nishitani T, "et al." |title=Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs. |journal=Biochem. Biophys. Res. Commun. |volume=292 |issue= 1 |pages= 256–62 |year= 2002 |pmid= 11890701 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=He H, Dang Y, Dai F, "et al." |title=Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. |journal=J. Biol. Chem. |volume=278 |issue= 31 |pages= 29278–87 |year= 2003 |pmid= 12740394 |doi= 10.1074/jbc.M303800200
*cite journal | author=Difilippantonio S, Chen Y, Pietas A, "et al." |title=Gene expression profiles in human non-small and small-cell lung cancers. |journal=Eur. J. Cancer |volume=39 |issue= 13 |pages= 1936–47 |year= 2003 |pmid= 12932674 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Yang YS, Song HD, Peng YD, "et al." |title=The gene expression profiling of sporadic pheochromocytoma and novel full-length cDNAs cloning. |journal=Endocr. Relat. Cancer |volume=10 |issue= 4 |pages= 621–7 |year= 2004 |pmid= 14713272 |doi=
*cite journal | author=Tanida I, Sou YS, Ezaki J, "et al." |title=HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. |journal=J. Biol. Chem. |volume=279 |issue= 35 |pages= 36268–76 |year= 2004 |pmid= 15187094 |doi= 10.1074/jbc.M401461200
*cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004
*cite journal | author=Tanida I, Ueno T, Kominami E |title=Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes. |journal=J. Biol. Chem. |volume=279 |issue= 46 |pages= 47704–10 |year= 2005 |pmid= 15355958 |doi= 10.1074/jbc.M407016200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704PBB_Controls
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