RAD51L3

RAD51-like 3 (S. cerevisiae), also known as RAD51L3, is a human gene.cite web | title = Entrez Gene: RAD51L3 RAD51-like 3 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5892| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, which are known to be involved in the homologous recombination and repair of DNA. This protein forms a complex with several other members of the RAD51 family, including RAD51L1, RAD51L2, and XRCC2. The protein complex formed with this protein has been shown to catalyze homologous pairing between single- and double-stranded DNA, and is thought to play a role in the early stage of recombinational repair of DNA. Several alternatively spliced transcript variants of this gene have been described, but the biological validity of some of them has not been determined.cite web | title = Entrez Gene: RAD51L3 RAD51-like 3 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5892| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Cartwright R, Dunn AM, Simpson PJ, "et al." |title=Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family. |journal=Nucleic Acids Res. |volume=26 |issue= 7 |pages= 1653–9 |year= 1998 |pmid= 9512535 |doi=
*cite journal | author=Pittman DL, Weinberg LR, Schimenti JC |title=Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene. |journal=Genomics |volume=49 |issue= 1 |pages= 103–11 |year= 1998 |pmid= 9570954 |doi= 10.1006/geno.1998.5226
*cite journal | author=Kawabata M, Saeki K |title=Multiple alternative transcripts of the human homologue of the mouse TRAD/R51H3/RAD51D gene, a member of the rec A/RAD51 gene family. |journal=Biochem. Biophys. Res. Commun. |volume=257 |issue= 1 |pages= 156–62 |year= 1999 |pmid= 10092526 |doi= 10.1006/bbrc.1999.0413
*cite journal | author=Schild D, Lio YC, Collins DW, "et al." |title=Evidence for simultaneous protein interactions between human Rad51 paralogs. |journal=J. Biol. Chem. |volume=275 |issue= 22 |pages= 16443–9 |year= 2000 |pmid= 10749867 |doi= 10.1074/jbc.M001473200
*cite journal | author=Braybrooke JP, Spink KG, Thacker J, Hickson ID |title=The RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that forms a complex with XRCC2. |journal=J. Biol. Chem. |volume=275 |issue= 37 |pages= 29100–6 |year= 2000 |pmid= 10871607 |doi= 10.1074/jbc.M002075200
*cite journal | author=Miller KA, Yoshikawa DM, McConnell IR, "et al." |title=RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8406–11 |year= 2002 |pmid= 11744692 |doi= 10.1074/jbc.M108306200
*cite journal | author=Masson JY, Tarsounas MC, Stasiak AZ, "et al." |title=Identification and purification of two distinct complexes containing the five RAD51 paralogs. |journal=Genes Dev. |volume=15 |issue= 24 |pages= 3296–307 |year= 2002 |pmid= 11751635 |doi= 10.1101/gad.947001
*cite journal | author=Sigurdsson S, Van Komen S, Bussen W, "et al." |title=Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange. |journal=Genes Dev. |volume=15 |issue= 24 |pages= 3308–18 |year= 2002 |pmid= 11751636 |doi= 10.1101/gad.935501
*cite journal | author=Kurumizaka H, Ikawa S, Nakada M, "et al." |title=Homologous pairing and ring and filament structure formation activities of the human Xrcc2*Rad51D complex. |journal=J. Biol. Chem. |volume=277 |issue= 16 |pages= 14315–20 |year= 2002 |pmid= 11834724 |doi= 10.1074/jbc.M105719200
*cite journal | author=Wiese C, Collins DW, Albala JS, "et al." |title=Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells. |journal=Nucleic Acids Res. |volume=30 |issue= 4 |pages= 1001–8 |year= 2002 |pmid= 11842112 |doi=
*cite journal | author=Liu N, Schild D, Thelen MP, Thompson LH |title=Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells. |journal=Nucleic Acids Res. |volume=30 |issue= 4 |pages= 1009–15 |year= 2002 |pmid= 11842113 |doi=
*cite journal | author=Godthelp BC, Artwert F, Joenje H, Zdzienicka MZ |title=Impaired DNA damage-induced nuclear Rad51 foci formation uniquely characterizes Fanconi anemia group D1. |journal=Oncogene |volume=21 |issue= 32 |pages= 5002–5 |year= 2002 |pmid= 12118380 |doi= 10.1038/sj.onc.1205656
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Braybrooke JP, Li JL, Wu L, "et al." |title=Functional interaction between the Bloom's syndrome helicase and the RAD51 paralog, RAD51L3 (RAD51D). |journal=J. Biol. Chem. |volume=278 |issue= 48 |pages= 48357–66 |year= 2004 |pmid= 12975363 |doi= 10.1074/jbc.M308838200
*cite journal | author=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance. |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8
*cite journal | author=Tarsounas M, Davies AA, West SC |title=RAD51 localization and activation following DNA damage. |journal=Philos. Trans. R. Soc. Lond., B, Biol. Sci. |volume=359 |issue= 1441 |pages= 87–93 |year= 2004 |pmid= 15065660 |doi= 10.1098/rstb.2003.1368
*cite journal | author=Tarsounas M, Muñoz P, Claas A, "et al." |title=Telomere maintenance requires the RAD51D recombination/repair protein. |journal=Cell |volume=117 |issue= 3 |pages= 337–47 |year= 2004 |pmid= 15109494 |doi=
*cite journal | author=Hussain S, Wilson JB, Medhurst AL, "et al." |title=Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. |journal=Hum. Mol. Genet. |volume=13 |issue= 12 |pages= 1241–8 |year= 2004 |pmid= 15115758 |doi= 10.1093/hmg/ddh135
*cite journal | author=Rodríguez-López R, Osorio A, Ribas G, "et al." |title=The variant E233G of the RAD51D gene could be a low-penetrance allele in high-risk breast cancer families without BRCA1/2 mutations. |journal=Int. J. Cancer |volume=110 |issue= 6 |pages= 845–9 |year= 2004 |pmid= 15170666 |doi= 10.1002/ijc.20169
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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