HEXIM1

Hexamethylene bis-acetamide inducible 1, also known as HEXIM1, is a human gene.cite web | title = Entrez Gene: HEXIM1 hexamethylene bis-acetamide inducible 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10614| accessdate = ]

PBB_Summary
section_title =
summary_text = Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns.cite web | title = Entrez Gene: HEXIM1 hexamethylene bis-acetamide inducible 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10614| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wolff A |title= [Problem of occupational disability hazards] |journal=Lebensversicherungs Medizin |volume=28 |issue= 3 |pages= 76–7 |year= 1976 |pmid= 9544 |doi=
*cite journal | author=Dias Neto E, Correa RG, Verjovski-Almeida S, "et al." |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=
*cite journal | author=Huang F, Wagner M, Siddiqui MA |title=Structure, expression, and functional characterization of the mouse CLP-1 gene. |journal=Gene |volume=292 |issue= 1-2 |pages= 245–59 |year= 2002 |pmid= 12119119 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ouchida R, Kusuhara M, Shimizu N, "et al." |title=Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells. |journal=Genes Cells |volume=8 |issue= 2 |pages= 95–107 |year= 2003 |pmid= 12581153 |doi=
*cite journal | author=Michels AA, Nguyen VT, Fraldi A, "et al." |title=MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner. |journal=Mol. Cell. Biol. |volume=23 |issue= 14 |pages= 4859–69 |year= 2003 |pmid= 12832472 |doi=
*cite journal | author=Yik JH, Chen R, Nishimura R, "et al." |title=Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. |journal=Mol. Cell |volume=12 |issue= 4 |pages= 971–82 |year= 2003 |pmid= 14580347 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Paushkin SV, Patel M, Furia BS, "et al." |title=Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation. |journal=Cell |volume=117 |issue= 3 |pages= 311–21 |year= 2004 |pmid= 15109492 |doi=
*cite journal | author=Yik JH, Chen R, Pezda AC, "et al." |title=A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb. |journal=Mol. Cell. Biol. |volume=24 |issue= 12 |pages= 5094–105 |year= 2004 |pmid= 15169877 |doi= 10.1128/MCB.24.12.5094-5105.2004
*cite journal | author=Michels AA, Fraldi A, Li Q, "et al." |title=Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor. |journal=EMBO J. |volume=23 |issue= 13 |pages= 2608–19 |year= 2005 |pmid= 15201869 |doi= 10.1038/sj.emboj.7600275
*cite journal | author=Yik JH, Chen R, Pezda AC, Zhou Q |title=Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription. |journal=J. Biol. Chem. |volume=280 |issue= 16 |pages= 16368–76 |year= 2005 |pmid= 15713661 |doi= 10.1074/jbc.M500912200
*cite journal | author=Byers SA, Price JP, Cooper JJ, "et al." |title=HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK. |journal=J. Biol. Chem. |volume=280 |issue= 16 |pages= 16360–7 |year= 2005 |pmid= 15713662 |doi= 10.1074/jbc.M500424200
*cite journal | author=Schulte A, Czudnochowski N, Barboric M, "et al." |title=Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat. |journal=J. Biol. Chem. |volume=280 |issue= 26 |pages= 24968–77 |year= 2005 |pmid= 15855166 |doi= 10.1074/jbc.M501431200
*cite journal | author=Wittmann BM, Fujinaga K, Deng H, "et al." |title=The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1. |journal=Oncogene |volume=24 |issue= 36 |pages= 5576–88 |year= 2005 |pmid= 15940264 |doi= 10.1038/sj.onc.1208728
*cite journal | author=Shimizu N, Ouchida R, Yoshikawa N, "et al." |title=HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 24 |pages= 8555–60 |year= 2005 |pmid= 15941832 |doi= 10.1073/pnas.0409863102
*cite journal | author=Li Q, Price JP, Byers SA, "et al." |title=Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186. |journal=J. Biol. Chem. |volume=280 |issue= 31 |pages= 28819–26 |year= 2005 |pmid= 15965233 |doi= 10.1074/jbc.M502712200
*cite journal | author=Fraldi A, Varrone F, Napolitano G, "et al." |title=Inhibition of Tat activity by the HEXIM1 protein. |journal=Retrovirology |volume=2 |issue= |pages= 42 |year= 2006 |pmid= 15992410 |doi= 10.1186/1742-4690-2-42
*cite journal | author=Dulac C, Michels AA, Fraldi A, "et al." |title=Transcription-dependent association of multiple positive transcription elongation factor units to a HEXIM multimer. |journal=J. Biol. Chem. |volume=280 |issue= 34 |pages= 30619–29 |year= 2005 |pmid= 15994294 |doi= 10.1074/jbc.M502471200
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

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