PRKRA

PRKRA

Protein kinase, interferon-inducible double stranded RNA dependent activator, also known as PRKRA,or PACT is a human gene.cite web | title = Entrez Gene: PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8575| accessdate = ]

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References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Simons A, Melamed-Bessudo C, Wolkowicz R, "et al." |title=PACT: cloning and characterization of a cellular p53 binding protein that interacts with Rb. |journal=Oncogene |volume=14 |issue= 2 |pages= 145–55 |year= 1997 |pmid= 9010216 |doi= 10.1038/sj.onc.1200825
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Patel RC, Sen GC |title=PACT, a protein activator of the interferon-induced protein kinase, PKR. |journal=EMBO J. |volume=17 |issue= 15 |pages= 4379–90 |year= 1998 |pmid= 9687506 |doi= 10.1093/emboj/17.15.4379
*cite journal | author=Ito T, Yang M, May WS |title=RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling. |journal=J. Biol. Chem. |volume=274 |issue= 22 |pages= 15427–32 |year= 1999 |pmid= 10336432 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=Horng T, Barton GM, Medzhitov R |title=TIR
journal=Nat. Immunol. |volume=2 |issue= 9 |pages= 835–41 |year= 2001 |pmid= 11526399 |doi= 10.1038/ni0901-835

*cite journal | author=Huang X, Hutchins B, Patel RC |title=The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR). |journal=Biochem. J. |volume=366 |issue= Pt 1 |pages= 175–86 |year= 2002 |pmid= 11985496 |doi= 10.1042/BJ20020204
*cite journal | author=Peters GA, Khoo D, Mohr I, Sen GC |title=Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein. |journal=J. Virol. |volume=76 |issue= 21 |pages= 11054–64 |year= 2002 |pmid= 12368348 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Yang M, Ito T, May WS |title=A novel role for RAX, the cellular activator of PKR, in synergistically stimulating SV40 large T antigen-dependent gene expression. |journal=J. Biol. Chem. |volume=278 |issue= 40 |pages= 38325–32 |year= 2003 |pmid= 12874289 |doi= 10.1074/jbc.M303420200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Bennett RL, Blalock WL, May WS |title=Serine 18 phosphorylation of RAX, the PKR activator, is required for PKR activation and consequent translation inhibition. |journal=J. Biol. Chem. |volume=279 |issue= 41 |pages= 42687–93 |year= 2004 |pmid= 15299031 |doi= 10.1074/jbc.M403321200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Lee Y, Hur I, Park SY, "et al." |title=The role of PACT in the RNA silencing pathway. |journal=EMBO J. |volume=25 |issue= 3 |pages= 522–32 |year= 2006 |pmid= 16424907 |doi= 10.1038/sj.emboj.7600942
*cite journal | author=Bennett RL, Blalock WL, Abtahi DM, "et al." |title=RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection. |journal=Blood |volume=108 |issue= 3 |pages= 821–9 |year= 2006 |pmid= 16861340 |doi= 10.1182/blood-2005-11-006817

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