SMARCE1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1, also known as SMARCE1, is a human gene.cite web | title = Entrez Gene: SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6605| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.cite web | title = Entrez Gene: SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6605| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Martens JA, Winston F |title=Recent advances in understanding chromatin remodeling by Swi/Snf complexes. |journal=Curr. Opin. Genet. Dev. |volume=13 |issue= 2 |pages= 136–42 |year= 2003 |pmid= 12672490 |doi=
*cite journal | author=Wang W, Côté J, Xue Y, "et al." |title=Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. |journal=EMBO J. |volume=15 |issue= 19 |pages= 5370–82 |year= 1996 |pmid= 8895581 |doi=
*cite journal | author=Wang W, Chi T, Xue Y, "et al." |title=Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 2 |pages= 492–8 |year= 1998 |pmid= 9435219 |doi=
*cite journal | author=Cho H, Orphanides G, Sun X, "et al." |title=A human RNA polymerase II complex containing factors that modify chromatin structure. |journal=Mol. Cell. Biol. |volume=18 |issue= 9 |pages= 5355–63 |year= 1998 |pmid= 9710619 |doi=
*cite journal | author=Phelan ML, Sif S, Narlikar GJ, Kingston RE |title=Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. |journal=Mol. Cell |volume=3 |issue= 2 |pages= 247–53 |year= 1999 |pmid= 10078207 |doi=
*cite journal | author=Xue Y, Canman JC, Lee CS, "et al." |title=The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 24 |pages= 13015–20 |year= 2001 |pmid= 11078522 |doi= 10.1073/pnas.240208597
*cite journal | author=Decristofaro MF, Betz BL, Rorie CJ, "et al." |title=Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies. |journal=J. Cell. Physiol. |volume=186 |issue= 1 |pages= 136–45 |year= 2001 |pmid= 11147808 |doi= 10.1002/1097-4652(200101)186:1<136::AID-JCP1010>3.0.CO;2-4 |doilabel=10.1002/1097-4652(200101)186:1136::AID-JCP10103.0.CO;2-4
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=Kato H, Tjernberg A, Zhang W, "et al." |title=SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones. |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 5498–505 |year= 2002 |pmid= 11734557 |doi= 10.1074/jbc.M108702200
*cite journal | author=Chi TH, Wan M, Zhao K, "et al." |title=Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. |journal=Nature |volume=418 |issue= 6894 |pages= 195–9 |year= 2002 |pmid= 12110891 |doi= 10.1038/nature00876
*cite journal | author=Belandia B, Orford RL, Hurst HC, Parker MG |title=Targeting of SWI/SNF chromatin remodelling complexes to estrogen-responsive genes. |journal=EMBO J. |volume=21 |issue= 15 |pages= 4094–103 |year= 2002 |pmid= 12145209 |doi=
*cite journal | author=Battaglioli E, Andrés ME, Rose DW, "et al." |title=REST repression of neuronal genes requires components of the hSWI.SNF complex. |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 41038–45 |year= 2002 |pmid= 12192000 |doi= 10.1074/jbc.M205691200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Baker KM, Wei G, Schaffner AE, Ostrowski MC |title=Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter. |journal=J. Biol. Chem. |volume=278 |issue= 20 |pages= 17876–84 |year= 2003 |pmid= 12637547 |doi= 10.1074/jbc.M209480200
*cite journal | author=Kitagawa H, Fujiki R, Yoshimura K, "et al." |title=The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. |journal=Cell |volume=113 |issue= 7 |pages= 905–17 |year= 2003 |pmid= 12837248 |doi=
*cite journal | author=Hsiao PW, Fryer CJ, Trotter KW, "et al." |title=BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation. |journal=Mol. Cell. Biol. |volume=23 |issue= 17 |pages= 6210–20 |year= 2003 |pmid= 12917342 |doi=
*cite journal | author=Wu K, Bottazzi ME, de la Fuente C, "et al." |title=Protein profile of tax-associated complexes. |journal=J. Biol. Chem. |volume=279 |issue= 1 |pages= 495–508 |year= 2004 |pmid= 14530271 |doi= 10.1074/jbc.M310069200
*cite journal | author=Millar JK, Christie S, Porteous DJ |title=Yeast two-hybrid screens implicate DISC1 in brain development and function. |journal=Biochem. Biophys. Res. Commun. |volume=311 |issue= 4 |pages= 1019–25 |year= 2004 |pmid= 14623284 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285

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