AIP (gene)

AIP (gene)

Aryl hydrocarbon receptor interacting protein, also known as AIP,XAP2 or AHRA 9 is a human gene.cite web | title = Entrez Gene: AIP aryl hydrocarbon receptor interacting protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9049| accessdate = ]

PBB_Summary
section_title =
summary_text = AIP may play a positive role in AHR-mediated signalling possibly by influencing its receptivity for ligand and/or its nuclear targeting. AIP is the cellular negative regulator of the HBV X protein.cite web | title = Entrez Gene: AIP aryl hydrocarbon receptor interacting protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9049| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Chen HS, Perdew GH |title=Subunit composition of the heteromeric cytosolic aryl hydrocarbon receptor complex. |journal=J. Biol. Chem. |volume=269 |issue= 44 |pages= 27554–8 |year= 1994 |pmid= 7961671 |doi=
*cite journal | author=Kuzhandaivelu N, Cong YS, Inouye C, "et al." |title=XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation. |journal=Nucleic Acids Res. |volume=24 |issue= 23 |pages= 4741–50 |year= 1997 |pmid= 8972861 |doi=
*cite journal | author=Ma Q, Whitlock JP |title=A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. |journal=J. Biol. Chem. |volume=272 |issue= 14 |pages= 8878–84 |year= 1997 |pmid= 9083006 |doi=
*cite journal | author=Carver LA, Bradfield CA |title=Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. |journal=J. Biol. Chem. |volume=272 |issue= 17 |pages= 11452–6 |year= 1997 |pmid= 9111057 |doi=
*cite journal | author=Meyer BK, Pray-Grant MG, Vanden Heuvel JP, Perdew GH |title=Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. |journal=Mol. Cell. Biol. |volume=18 |issue= 2 |pages= 978–88 |year= 1998 |pmid= 9447995 |doi=
*cite journal | author=Carver LA, LaPres JJ, Jain S, "et al." |title=Characterization of the Ah receptor-associated protein, ARA9. |journal=J. Biol. Chem. |volume=273 |issue= 50 |pages= 33580–7 |year= 1999 |pmid= 9837941 |doi=
*cite journal | author=Gadelha MR, Une KN, Rohde K, "et al." |title=Isolated familial somatotropinomas: establishment of linkage to chromosome 11q13.1-11q13.3 and evidence for a potential second locus at chromosome 2p16-12. |journal=J. Clin. Endocrinol. Metab. |volume=85 |issue= 2 |pages= 707–14 |year= 2000 |pmid= 10690880 |doi=
*cite journal | author=Petrulis JR, Hord NG, Perdew GH |title=Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2. |journal=J. Biol. Chem. |volume=275 |issue= 48 |pages= 37448–53 |year= 2001 |pmid= 10986286 |doi= 10.1074/jbc.M006873200
*cite journal | author=Kazlauskas A, Poellinger L, Pongratz I |title=The immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptor. |journal=J. Biol. Chem. |volume=275 |issue= 52 |pages= 41317–24 |year= 2001 |pmid= 11013261 |doi= 10.1074/jbc.M007765200
*cite journal | author=Kazlauskas A, Sundström S, Poellinger L, Pongratz I |title=The hsp90 chaperone complex regulates intracellular localization of the dioxin receptor. |journal=Mol. Cell. Biol. |volume=21 |issue= 7 |pages= 2594–607 |year= 2001 |pmid= 11259606 |doi= 10.1128/MCB.21.7.2594-2607.2001
*cite journal | author=Kazlauskas A, Poellinger L, Pongratz I |title=Two distinct regions of the immunophilin-like protein XAP2 regulate dioxin receptor function and interaction with hsp90. |journal=J. Biol. Chem. |volume=277 |issue= 14 |pages= 11795–801 |year= 2002 |pmid= 11805120 |doi= 10.1074/jbc.M200053200
*cite journal | author=Patterson CE, Gao J, Rooney AP, Davis EC |title=Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family. |journal=Genomics |volume=79 |issue= 6 |pages= 881–9 |year= 2002 |pmid= 12036304 |doi= 10.1006/geno.2002.6777
*cite journal | author=Berg P, Pongratz I |title=Two parallel pathways mediate cytoplasmic localization of the dioxin (aryl hydrocarbon) receptor. |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 32310–9 |year= 2002 |pmid= 12065584 |doi= 10.1074/jbc.M203351200
*cite journal | author=Dull AB, Carlson DB, Petrulis JR, Perdew GH |title=Characterization of the phosphorylation status of the hepatitis B virus X-associated protein 2. |journal=Arch. Biochem. Biophys. |volume=406 |issue= 2 |pages= 209–21 |year= 2002 |pmid= 12361709 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Sumanasekera WK, Tien ES, Turpey R, "et al." |title=Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2. |journal=J. Biol. Chem. |volume=278 |issue= 7 |pages= 4467–73 |year= 2003 |pmid= 12482853 |doi= 10.1074/jbc.M211261200
*cite journal | author=Zhao Y, Meng XM, Wei YJ, "et al." |title=Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I. |journal=J. Mol. Med. |volume=81 |issue= 5 |pages= 297–304 |year= 2004 |pmid= 12721663 |doi= 10.1007/s00109-003-0427-x
*cite journal | author=Lees MJ, Peet DJ, Whitelaw ML |title=Defining the role for XAP2 in stabilization of the dioxin receptor. |journal=J. Biol. Chem. |volume=278 |issue= 38 |pages= 35878–88 |year= 2003 |pmid= 12837759 |doi= 10.1074/jbc.M302430200
*cite journal | author=Yano M, Terada K, Mori M |title=AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins. |journal=J. Cell Biol. |volume=163 |issue= 1 |pages= 45–56 |year= 2003 |pmid= 14557246 |doi= 10.1083/jcb.200305051
*cite journal | author=Ramadoss P, Petrulis JR, Hollingshead BD, "et al." |title=Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes. |journal=Biochemistry |volume=43 |issue= 3 |pages= 700–9 |year= 2004 |pmid= 14730974 |doi= 10.1021/bi035827v

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