RPLP0

Ribosomal protein, large, P0, also known as RPLP0, is a human gene.cite web | title = Entrez Gene: RPLP0 ribosomal protein, large, P0| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6175| accessdate = ]

PBB_Summary
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summary_text = Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.cite web | title = Entrez Gene: RPLP0 ribosomal protein, large, P0| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6175| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wool IG, Chan YL, Glück A |title=Structure and evolution of mammalian ribosomal proteins. |journal=Biochem. Cell Biol. |volume=73 |issue= 11-12 |pages= 933–47 |year= 1996 |pmid= 8722009 |doi=
*cite journal | author=Dawson SJ, White LA |title=Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. |journal=J. Infect. |volume=24 |issue= 3 |pages= 317–20 |year= 1992 |pmid= 1602151 |doi=
*cite journal | author=Rich BE, Steitz JA |title=Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly. |journal=Mol. Cell. Biol. |volume=7 |issue= 11 |pages= 4065–74 |year= 1988 |pmid= 3323886 |doi=
*cite journal | author=Towbin H, Ramjoué HP, Kuster H, "et al." |title=Monoclonal antibodies against eucaryotic ribosomes. Use to characterize a ribosomal protein not previously identified and antigenically related to the acidic phosphoproteins P1/P2. |journal=J. Biol. Chem. |volume=257 |issue= 21 |pages= 12709–15 |year= 1982 |pmid= 6182142 |doi=
*cite journal | author=Kato S, Sekine S, Oh SW, "et al." |title=Construction of a human full-length cDNA bank. |journal=Gene |volume=150 |issue= 2 |pages= 243–50 |year= 1995 |pmid= 7821789 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Kenmochi N, Kawaguchi T, Rozen S, "et al." |title=A map of 75 human ribosomal protein genes. |journal=Genome Res. |volume=8 |issue= 5 |pages= 509–23 |year= 1998 |pmid= 9582194 |doi=
*cite journal | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi=
*cite journal | author=Tchórzewski M, Boldyreff B, Issinger O, Grankowski N |title=Analysis of the protein-protein interactions between the human acidic ribosomal P-proteins: evaluation by the two hybrid system. |journal=Int. J. Biochem. Cell Biol. |volume=32 |issue= 7 |pages= 737–46 |year= |pmid= 10856704 |doi=
*cite journal | author=Chan SH, Hung FS, Chan DS, Shaw PC |title=Trichosanthin interacts with acidic ribosomal proteins P0 and P1 and mitotic checkpoint protein MAD2B. |journal=Eur. J. Biochem. |volume=268 |issue= 7 |pages= 2107–12 |year= 2001 |pmid= 11277934 |doi=
*cite journal | author=Uechi T, Tanaka T, Kenmochi N |title=A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders. |journal=Genomics |volume=72 |issue= 3 |pages= 223–30 |year= 2001 |pmid= 11401437 |doi= 10.1006/geno.2000.6470
*cite journal | author=Andersen JS, Lyon CE, Fox AH, "et al." |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tchórzewski M, Krokowski D, Rzeski W, "et al." |title=The subcellular distribution of the human ribosomal "stalk" components: P1, P2 and P0 proteins. |journal=Int. J. Biochem. Cell Biol. |volume=35 |issue= 2 |pages= 203–11 |year= 2003 |pmid= 12479870 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Shu H, Chen S, Bi Q, "et al." |title=Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line. |journal=Mol. Cell Proteomics |volume=3 |issue= 3 |pages= 279–86 |year= 2004 |pmid= 14729942 |doi= 10.1074/mcp.D300003-MCP200
*cite journal | author=Bouwmeester T, Bauch A, Ruffner H, "et al." |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086
*cite journal | author=Villacé P, Marión RM, Ortín J |title=The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs. |journal=Nucleic Acids Res. |volume=32 |issue= 8 |pages= 2411–20 |year= 2004 |pmid= 15121898 |doi= 10.1093/nar/gkh552

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