Barrier to autointegration factor 1

Barrier to autointegration factor 1

Barrier to autointegration factor 1, also known as BANF1, is a human gene.cite web | title = Entrez Gene: BANF1 barrier to autointegration factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8815| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene was identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The endogenous function of the protein is unknown. The protein forms a homodimer which localizes to the nucleus and is specifically associated with chromosomes during mitosis. This protein binds to DNA in a non-specific manner and studies in rodents suggest that it also binds to lamina-associated polypeptide 2, a component of the nuclear lamina.cite web | title = Entrez Gene: BANF1 barrier to autointegration factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8815| accessdate = ]

ee also

*retroviral integration

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Goldberg M, Harel A, Gruenbaum Y |title=The nuclear lamina: molecular organization and interaction with chromatin. |journal=Crit. Rev. Eukaryot. Gene Expr. |volume=9 |issue= 3-4 |pages= 285–93 |year= 2000 |pmid= 10651245 |doi=
*cite journal | author=Segura-Totten M, Wilson KL |title=BAF: roles in chromatin, nuclear structure and retrovirus integration. |journal=Trends Cell Biol. |volume=14 |issue= 5 |pages= 261–6 |year= 2004 |pmid= 15130582 |doi= 10.1016/j.tcb.2004.03.004
*cite journal | author=Van Maele B, Debyser Z |title=HIV-1 integration: an interplay between HIV-1 integrase, cellular and viral proteins. |journal=AIDS reviews |volume=7 |issue= 1 |pages= 26–43 |year= 2005 |pmid= 15875659 |doi=
*cite journal | author=Van Maele B, Busschots K, Vandekerckhove L, "et al." |title=Cellular co-factors of HIV-1 integration. |journal=Trends Biochem. Sci. |volume=31 |issue= 2 |pages= 98–105 |year= 2006 |pmid= 16403635 |doi= 10.1016/j.tibs.2005.12.002
*cite journal | author=Lee MS, Craigie R |title=Protection of retroviral DNA from autointegration: involvement of a cellular factor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 21 |pages= 9823–7 |year= 1994 |pmid= 7937898 |doi=
*cite journal | author=Lee MS, Craigie R |title=A previously unidentified host protein protects retroviral DNA from autointegration. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 4 |pages= 1528–33 |year= 1998 |pmid= 9465049 |doi=
*cite journal | author=Dear PH, Bankier AT, Piper MB |title=A high-resolution metric HAPPY map of human chromosome 14. |journal=Genomics |volume=48 |issue= 2 |pages= 232–41 |year= 1998 |pmid= 9521877 |doi= 10.1006/geno.1997.5140
*cite journal | author=Lynch RA, Piper M, Bankier A, "et al." |title=Genomic and functional map of the chromosome 14 t(12;14) breakpoint cluster region in uterine leiomyoma. |journal=Genomics |volume=52 |issue= 1 |pages= 17–26 |year= 1999 |pmid= 9740667 |doi= 10.1006/geno.1998.5406
*cite journal | author=Cai M, Huang Y, Zheng R, "et al." |title=Solution structure of the cellular factor BAF responsible for protecting retroviral DNA from autointegration. |journal=Nat. Struct. Biol. |volume=5 |issue= 10 |pages= 903–9 |year= 1998 |pmid= 9783751 |doi= 10.1038/2345
*cite journal | author=Furukawa K |title=LAP2 binding protein 1 (L2BP1/BAF) is a candidate mediator of LAP2-chromatin interaction. |journal=J. Cell. Sci. |volume=112 ( Pt 15) |issue= |pages= 2485–92 |year= 1999 |pmid= 10393804 |doi=
*cite journal | author=Zheng R, Ghirlando R, Lee MS, "et al." |title=Barrier-to-autointegration factor (BAF) bridges DNA in a discrete, higher-order nucleoprotein complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 16 |pages= 8997–9002 |year= 2000 |pmid= 10908652 |doi= 10.1073/pnas.150240197
*cite journal | author=Umland TC, Wei SQ, Craigie R, Davies DR |title=Structural basis of DNA bridging by barrier-to-autointegration factor. |journal=Biochemistry |volume=39 |issue= 31 |pages= 9130–8 |year= 2000 |pmid= 10924106 |doi=
*cite journal | author=Harris D, Engelman A |title=Both the structure and DNA binding function of the barrier-to-autointegration factor contribute to reconstitution of HIV type 1 integration in vitro. |journal=J. Biol. Chem. |volume=275 |issue= 50 |pages= 39671–7 |year= 2001 |pmid= 11005805 |doi= 10.1074/jbc.M002626200
*cite journal | author=Lee KK, Haraguchi T, Lee RS, "et al." |title=Distinct functional domains in emerin bind lamin A and DNA-bridging protein BAF. |journal=J. Cell. Sci. |volume=114 |issue= Pt 24 |pages= 4567–73 |year= 2002 |pmid= 11792821 |doi=
*cite journal | author=Haraguchi T, Koujin T, Segura-Totten M, "et al." |title=BAF is required for emerin assembly into the reforming nuclear envelope. |journal=J. Cell. Sci. |volume=114 |issue= Pt 24 |pages= 4575–85 |year= 2002 |pmid= 11792822 |doi=
*cite journal | author=Segura-Totten M, Kowalski AK, Craigie R, Wilson KL |title=Barrier-to-autointegration factor: major roles in chromatin decondensation and nuclear assembly. |journal=J. Cell Biol. |volume=158 |issue= 3 |pages= 475–85 |year= 2002 |pmid= 12163470 |doi= 10.1083/jcb.200202019
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Holaska JM, Lee KK, Kowalski AK, Wilson KL |title=Transcriptional repressor germ cell-less (GCL) and barrier to autointegration factor (BAF) compete for binding to emerin in vitro. |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 6969–75 |year= 2003 |pmid= 12493765 |doi= 10.1074/jbc.M208811200
*cite journal | author=Lin CW, Engelman A |title=The barrier-to-autointegration factor is a component of functional human immunodeficiency virus type 1 preintegration complexes. |journal=J. Virol. |volume=77 |issue= 8 |pages= 5030–6 |year= 2003 |pmid= 12663813 |doi=

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • BCLAF1 — BCL2 associated transcription factor 1, also known as BCLAF1, is a human gene.cite web | title = Entrez Gene: BCLAF1 BCL2 associated transcription factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Nuclear envelope — Human cell nucleus A nuclear envelope (NE) (also known as the perinuclear envelope, nuclear membrane, nucleolemma or karyotheca) is a double lipid bilayer that encloses the genetic material in eukaryotic cells. The nuclear envelope also serves as …   Wikipedia

  • Nuclear lamina — The nuclear lamina is a dense ( 30 to 100 nm thick) fibrillar network inside the nucleus of a eukaryotic cell. It is composed of intermediate filaments and membrane associated proteins. Besides providing mechanical support, the nuclear lamina… …   Wikipedia

  • Emerin — Emerin, together with MAN1, is a LEM domain containing integral membrane protein of the nuclear membrane in vertebrates. The function of MAN1 is not extensively known, but emerin is known to interact with nuclear lamins, barrier to… …   Wikipedia

  • LAP2alpha — Masse/Länge Primärstruktur 693 Aminosäuren …   Deutsch Wikipedia

  • Lamin — Als Lamine werden die Typ V Intermediärfilamente bezeichnet. Die Lamine findet man im Zellkern eukaryotischer Zellen, wo sie über eine Vielzahl von membrangebundenen Proteinen (z. B. Emerin) mit der inneren Kernmembran verankert sind. Wie für… …   Deutsch Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”