FANCG

FANCG

Fanconi anemia, complementation group G, also known as FANCG, is a human gene.cite web | title = Entrez Gene: FANCG Fanconi anemia, complementation group G| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2189| accessdate = ]

PBB_Summary
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summary_text = FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified. The FANCG gene is responsible for complementation group G.cite web | title = Entrez Gene: FANCG Fanconi anemia, complementation group G| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2189| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Liu N, Lamerdin JE, Tucker JD, "et al." |title=The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 17 |pages= 9232–7 |year= 1997 |pmid= 9256465 |doi=
*cite journal | author=Joenje H, Oostra AB, Wijker M, "et al." |title=Evidence for at least eight Fanconi anemia genes. |journal=Am. J. Hum. Genet. |volume=61 |issue= 4 |pages= 940–4 |year= 1997 |pmid= 9382107 |doi=
*cite journal | author=de Winter JP, Waisfisz Q, Rooimans MA, "et al." |title=The Fanconi anaemia group G gene FANCG is identical with XRCC9. |journal=Nat. Genet. |volume=20 |issue= 3 |pages= 281–3 |year= 1998 |pmid= 9806548 |doi= 10.1038/3093
*cite journal | author=Garcia-Higuera I, Kuang Y, Näf D, "et al." |title=Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex. |journal=Mol. Cell. Biol. |volume=19 |issue= 7 |pages= 4866–73 |year= 1999 |pmid= 10373536 |doi=
*cite journal | author=Jelesko JG, Harper R, Furuya M, Gruissem W |title=Rare germinal unequal crossing-over leading to recombinant gene formation and gene duplication in Arabidopsis thaliana. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 18 |pages= 10302–7 |year= 1999 |pmid= 10468603 |doi=
*cite journal | author=Waisfisz Q, de Winter JP, Kruyt FA, "et al." |title=A physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCA. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 18 |pages= 10320–5 |year= 1999 |pmid= 10468606 |doi=
*cite journal | author=Kruyt FA, Abou-Zahr F, Mok H, Youssoufian H |title=Resistance to mitomycin C requires direct interaction between the Fanconi anemia proteins FANCA and FANCG in the nucleus through an arginine-rich domain. |journal=J. Biol. Chem. |volume=274 |issue= 48 |pages= 34212–8 |year= 1999 |pmid= 10567393 |doi=
*cite journal | author=Reuter T, Herterich S, Bernhard O, "et al." |title=Strong FANCA/FANCG but weak FANCA/FANCC interaction in the yeast 2-hybrid system. |journal=Blood |volume=95 |issue= 2 |pages= 719–20 |year= 2000 |pmid= 10627486 |doi=
*cite journal | author=Huber PA, Medhurst AL, Youssoufian H, Mathew CG |title=Investigation of Fanconi anemia protein interactions by yeast two-hybrid analysis. |journal=Biochem. Biophys. Res. Commun. |volume=268 |issue= 1 |pages= 73–7 |year= 2000 |pmid= 10652215 |doi= 10.1006/bbrc.1999.2055
*cite journal | author=Yamada T, Tachibana A, Shimizu T, "et al." |title=Novel mutations of the FANCG gene causing alternative splicing in Japanese Fanconi anemia. |journal=J. Hum. Genet. |volume=45 |issue= 3 |pages= 159–66 |year= 2000 |pmid= 10807541 |doi=
*cite journal | author=Kuang Y, Garcia-Higuera I, Moran A, "et al." |title=Carboxy terminal region of the Fanconi anemia protein, FANCG/XRCC9, is required for functional activity. |journal=Blood |volume=96 |issue= 5 |pages= 1625–32 |year= 2000 |pmid= 10961856 |doi=
*cite journal | author=Garcia-Higuera I, Kuang Y, Denham J, D'Andrea AD |title=The fanconi anemia proteins FANCA and FANCG stabilize each other and promote the nuclear accumulation of the Fanconi anemia complex. |journal=Blood |volume=96 |issue= 9 |pages= 3224–30 |year= 2000 |pmid= 11050007 |doi=
*cite journal | author=de Winter JP, van der Weel L, de Groot J, "et al." |title=The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG. |journal=Hum. Mol. Genet. |volume=9 |issue= 18 |pages= 2665–74 |year= 2000 |pmid= 11063725 |doi=
*cite journal | author=Demuth I, Wlodarski M, Tipping AJ, "et al." |title=Spectrum of mutations in the Fanconi anaemia group G gene, FANCG/XRCC9. |journal=Eur. J. Hum. Genet. |volume=8 |issue= 11 |pages= 861–8 |year= 2000 |pmid= 11093276 |doi= 10.1038/sj.ejhg.5200552
*cite journal | author=Medhurst AL, Huber PA, Waisfisz Q, "et al." |title=Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway. |journal=Hum. Mol. Genet. |volume=10 |issue= 4 |pages= 423–9 |year= 2001 |pmid= 11157805 |doi=
*cite journal | author=McMahon LW, Sangerman J, Goodman SR, "et al." |title=Human alpha spectrin II and the FANCA, FANCC, and FANCG proteins bind to DNA containing psoralen interstrand cross-links. |journal=Biochemistry |volume=40 |issue= 24 |pages= 7025–34 |year= 2001 |pmid= 11401546 |doi=
*cite journal | author=Yagasaki H, Adachi D, Oda T, "et al." |title=A cytoplasmic serine protein kinase binds and may regulate the Fanconi anemia protein FANCA. |journal=Blood |volume=98 |issue= 13 |pages= 3650–7 |year= 2002 |pmid= 11739169 |doi=
*cite journal | author=Futaki M, Igarashi T, Watanabe S, "et al." |title=The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage. |journal=Carcinogenesis |volume=23 |issue= 1 |pages= 67–72 |year= 2002 |pmid= 11756225 |doi=
*cite journal | author=van de Vrugt HJ, Koomen M, Berns MA, "et al." |title=Characterization, expression and complex formation of the murine Fanconi anaemia gene product Fancg. |journal=Genes Cells |volume=7 |issue= 3 |pages= 333–42 |year= 2002 |pmid= 11918676 |doi=
*cite journal | author=Pace P, Johnson M, Tan WM, "et al." |title=FANCE: the link between Fanconi anaemia complex assembly and activity. |journal=EMBO J. |volume=21 |issue= 13 |pages= 3414–23 |year= 2002 |pmid= 12093742 |doi= 10.1093/emboj/cdf355

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