SILV

Silver homolog (mouse), also known as SILV, is a human gene.cite web | title = Entrez Gene: SILV silver homolog (mouse)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6490| accessdate = ] It gene product called silver, ME20, gp100 or Pmel17 is 100 kDa type I transmembrane protein. Its processing results in the formation of non-pathological aggregates that form the melanosomal striation. PBB_Summary
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References

Further reading

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*cite journal | author=Aplan PD, Lombardi DP, Kirsch IR |title=Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia. |journal=Mol. Cell. Biol. |volume=11 |issue= 11 |pages= 5462–9 |year= 1991 |pmid= 1922059 |doi=
*cite journal | author=Kwon BS, Chintamaneni C, Kozak CA, "et al." |title=A melanocyte-specific gene, Pmel 17, maps near the silver coat color locus on mouse chromosome 10 and is in a syntenic region on human chromosome 12. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 20 |pages= 9228–32 |year= 1991 |pmid= 1924386 |doi=
*cite journal | author=Brown L, Cheng JT, Chen Q, "et al." |title=Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia. |journal=EMBO J. |volume=9 |issue= 10 |pages= 3343–51 |year= 1990 |pmid= 2209547 |doi=
*cite journal | author=Aplan PD, Lombardi DP, Ginsberg AM, "et al." |title=Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity. |journal=Science |volume=250 |issue= 4986 |pages= 1426–9 |year= 1991 |pmid= 2255914 |doi=
*cite journal | author=Adema GJ, de Boer AJ, Vogel AM, "et al." |title=Molecular characterization of the melanocyte lineage-specific antigen gp100. |journal=J. Biol. Chem. |volume=269 |issue= 31 |pages= 20126–33 |year= 1994 |pmid= 7519602 |doi=
*cite journal | author=Kawakami Y, Eliyahu S, Delgado CH, "et al." |title=Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 14 |pages= 6458–62 |year= 1994 |pmid= 8022805 |doi=
*cite journal | author=Maresh GA, Marken JS, Neubauer M, "et al." |title=Cloning and expression of the gene for the melanoma-associated ME20 antigen. |journal=DNA Cell Biol. |volume=13 |issue= 2 |pages= 87–95 |year= 1994 |pmid= 8179825 |doi=
*cite journal | author=Bailin T, Lee ST, Spritz RA |title=Genomic organization and sequence of D12S53E (Pmel 17), the human homologue of the mouse silver (si) locus. |journal=J. Invest. Dermatol. |volume=106 |issue= 1 |pages= 24–7 |year= 1996 |pmid= 8592076 |doi=
*cite journal | author=Chakraborty AK, Platt JT, Kim KK, "et al." |title=Polymerization of 5,6-dihydroxyindole-2-carboxylic acid to melanin by the pmel 17/silver locus protein. |journal=Eur. J. Biochem. |volume=236 |issue= 1 |pages= 180–8 |year= 1996 |pmid= 8617263 |doi=
*cite journal | author=Kim KK, Youn BS, Heng HH, "et al." |title=Genomic organization and FISH mapping of human Pmel 17, the putative silver locus. |journal=Pigment Cell Res. |volume=9 |issue= 1 |pages= 42–8 |year= 1996 |pmid= 8739560 |doi=
*cite journal | author=Chi DD, Merchant RE, Rand R, "et al." |title=Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas. |journal=Am. J. Pathol. |volume=150 |issue= 6 |pages= 2143–52 |year= 1997 |pmid= 9176405 |doi=
*cite journal | author=Wagner SN, Wagner C, Schultewolter T, Goos M |title=Analysis of Pmel17/gp100 expression in primary human tissue specimens: implications for melanoma immuno- and gene-therapy. |journal=Cancer Immunol. Immunother. |volume=44 |issue= 4 |pages= 239–47 |year= 1997 |pmid= 9222283 |doi=
*cite journal | author=Curry BJ, Myers K, Hersey P |title=Polymerase chain reaction detection of melanoma cells in the circulation: relation to clinical stage, surgical treatment, and recurrence from melanoma. |journal=J. Clin. Oncol. |volume=16 |issue= 5 |pages= 1760–9 |year= 1998 |pmid= 9586889 |doi=
*cite journal | author=Lupetti R, Pisarra P, Verrecchia A, "et al." |title=Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage. |journal=J. Exp. Med. |volume=188 |issue= 6 |pages= 1005–16 |year= 1998 |pmid= 9743519 |doi=
*cite journal | author=Lukowsky A, Bellmann B, Ringk A, "et al." |title=Detection of melanoma micrometastases in the sentinel lymph node and in nonsentinel nodes by tyrosinase polymerase chain reaction. |journal=J. Invest. Dermatol. |volume=113 |issue= 4 |pages= 554–9 |year= 1999 |pmid= 10504440 |doi= 10.1046/j.1523-1747.1999.00719.x
*cite journal | author=Raposo G, Tenza D, Murphy DM, "et al." |title=Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells. |journal=J. Cell Biol. |volume=152 |issue= 4 |pages= 809–24 |year= 2001 |pmid= 11266471 |doi=
*cite journal | author=Virador V, Matsunaga N, Matsunaga J, "et al." |title=Production of melanocyte-specific antibodies to human melanosomal proteins: expression patterns in normal human skin and in cutaneous pigmented lesions. |journal=Pigment Cell Res. |volume=14 |issue= 4 |pages= 289–97 |year= 2002 |pmid= 11549113 |doi=
*cite journal | author=Berson JF, Harper DC, Tenza D, "et al." |title=Pmel17 initiates premelanosome morphogenesis within multivesicular bodies. |journal=Mol. Biol. Cell |volume=12 |issue= 11 |pages= 3451–64 |year= 2002 |pmid= 11694580 |doi=
*cite journal | author=Sensi M, Pellegatta S, Vegetti C, "et al." |title=Identification of a novel gp100/pMel17 peptide presented by HLA-A*6801 and recognized on human melanoma by cytolytic T cell clones. |journal=Tissue Antigens |volume=59 |issue= 4 |pages= 273–9 |year= 2003 |pmid= 12135425 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899

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