Involucrin

Involucrin

Involucrin, also known as IVL, is a human gene.cite web | title = Entrez Gene: IVL involucrin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3713| accessdate = ]

PBB_Summary
section_title =
summary_text = Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.cite web | title = Entrez Gene: IVL involucrin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3713| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Eckert RL, Crish JF, Efimova T, "et al." |title=Regulation of involucrin gene expression. |journal=J. Invest. Dermatol. |volume=123 |issue= 1 |pages= 13–22 |year= 2004 |pmid= 15191537 |doi= 10.1111/j.0022-202X.2004.22723.x
*cite journal | author=Rice RH, Green H |title=Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions. |journal=Cell |volume=18 |issue= 3 |pages= 681–94 |year= 1980 |pmid= 42494 |doi=
*cite journal | author=Yaffe MB, Beegen H, Eckert RL |title=Biophysical characterization of involucrin reveals a molecule ideally suited to function as an intermolecular cross-bridge of the keratinocyte cornified envelope. |journal=J. Biol. Chem. |volume=267 |issue= 17 |pages= 12233–8 |year= 1992 |pmid= 1601889 |doi=
*cite journal | author=Simon M, Green H |title=The glutamine residues reactive in transglutaminase-catalyzed cross-linking of involucrin. |journal=J. Biol. Chem. |volume=263 |issue= 34 |pages= 18093–8 |year= 1989 |pmid= 2461365 |doi=
*cite journal | author=Eckert RL, Green H |title=Structure and evolution of the human involucrin gene. |journal=Cell |volume=46 |issue= 4 |pages= 583–9 |year= 1986 |pmid= 2873896 |doi=
*cite journal | author=Heller M, Flemington E, Kieff E, Deininger P |title=Repeat arrays in cellular DNA related to the Epstein-Barr virus IR3 repeat. |journal=Mol. Cell. Biol. |volume=5 |issue= 3 |pages= 457–65 |year= 1985 |pmid= 2985954 |doi=
*cite journal | author=Welter JF, Crish JF, Agarwal C, Eckert RL |title=Fos-related antigen (Fra-1), junB, and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity. |journal=J. Biol. Chem. |volume=270 |issue= 21 |pages= 12614–22 |year= 1995 |pmid= 7759510 |doi=
*cite journal | author=Volz A, Korge BP, Compton JG, "et al." |title=Physical mapping of a functional cluster of epidermal differentiation genes on chromosome 1q21. |journal=Genomics |volume=18 |issue= 1 |pages= 92–9 |year= 1994 |pmid= 8276421 |doi= 10.1006/geno.1993.1430
*cite journal | author=Takahashi H, Iizuka H |title=Analysis of the 5'-upstream promoter region of human involucrin gene: activation by 12-O-tetradecanoylphorbol-13-acetate. |journal=J. Invest. Dermatol. |volume=100 |issue= 1 |pages= 10–5 |year= 1993 |pmid= 8380829 |doi=
*cite journal | author=Lopez-Bayghen E, Vega A, Cadena A, "et al." |title=Transcriptional analysis of the 5'-noncoding region of the human involucrin gene. |journal=J. Biol. Chem. |volume=271 |issue= 1 |pages= 512–20 |year= 1996 |pmid= 8550612 |doi=
*cite journal | author=Takahashi H, Kobayashi H, Matsuo S, Iizuka H |title=Repression of involucrin gene expression by transcriptional enhancer factor 1 (TEF-1). |journal=Arch. Dermatol. Res. |volume=287 |issue= 8 |pages= 740–6 |year= 1996 |pmid= 8554386 |doi=
*cite journal | author=Steinert PM, Marekov LN |title=Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope. |journal=J. Biol. Chem. |volume=272 |issue= 3 |pages= 2021–30 |year= 1997 |pmid= 8999895 |doi=
*cite journal | author=Robinson NA, Lapic S, Welter JF, Eckert RL |title=S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes. |journal=J. Biol. Chem. |volume=272 |issue= 18 |pages= 12035–46 |year= 1997 |pmid= 9115270 |doi=
*cite journal | author=Ng DC, Su MJ, Kim R, Bikle DD |title=Regulation of involucrin gene expression by calcium in normal human keratinocytes. |journal=Front. Biosci. |volume=1 |issue= |pages= a16–24 |year= 2004 |pmid= 9159190 |doi=
*cite journal | author=Banks EB, Crish JF, Welter JF, Eckert RL |title=Characterization of human involucrin promoter distal regulatory region transcriptional activator elements-a role for Sp1 and AP1 binding sites. |journal=Biochem. J. |volume=331 ( Pt 1) |issue= |pages= 61–8 |year= 1998 |pmid= 9512462 |doi=
*cite journal | author=Marekov LN, Steinert PM |title=Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope. |journal=J. Biol. Chem. |volume=273 |issue= 28 |pages= 17763–70 |year= 1998 |pmid= 9651377 |doi=
*cite journal | author=Crish JF, Zaim TM, Eckert RL |title=The distal regulatory region of the human involucrin promoter is required for expression in epidermis. |journal=J. Biol. Chem. |volume=273 |issue= 46 |pages= 30460–5 |year= 1998 |pmid= 9804813 |doi=
*cite journal | author=Lee CH, Marekov LN, Kim S, "et al." |title=Small proline-rich protein 1 is the major component of the cell envelope of normal human oral keratinocytes. |journal=FEBS Lett. |volume=477 |issue= 3 |pages= 268–72 |year= 2000 |pmid= 10908733 |doi=
*cite journal | author=Candi E, Oddi S, Terrinoni A, "et al." |title=Transglutaminase 5 cross-links loricrin, involucrin, and small proline-rich proteins in vitro. |journal=J. Biol. Chem. |volume=276 |issue= 37 |pages= 35014–23 |year= 2001 |pmid= 11443109 |doi= 10.1074/jbc.M010157200
*cite journal | author=Crish JF, Bone F, Banks EB, Eckert RL |title=The human involucrin gene contains spatially distinct regulatory elements that regulate expression during early versus late epidermal differentiation. |journal=Oncogene |volume=21 |issue= 5 |pages= 738–47 |year= 2002 |pmid= 11850802 |doi= 10.1038/sj.onc.1205038

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • involucrin — Marker protein for keratinocyte differentiation first appearing in the upper spinous layer of the epidermis. Together with trichohyalin forms the scaffold for the cell envelope …   Dictionary of molecular biology

  • involucrin — A non–keratin soluble precursor of the highly cross linked protein known as the corneocyte envelope. [fr. L. involucrum, a wrapper] …   Medical dictionary

  • SPRR3 — Small proline rich protein 3, also known as SPRR3, is a human gene.cite web | title = Entrez Gene: SPRR3 small proline rich protein 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=6707| accessdate = ] PBB …   Wikipedia

  • LOR (gene) — Loricrin, also known as LOR, is a human gene.cite web | title = Entrez Gene: LOR loricrin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=4014| accessdate = ] PBB Summary section title = summary text = This …   Wikipedia

  • Envoplakin — Envoplakin, also known as EVPL, is a human gene.cite web | title = Entrez Gene: EVPL envoplakin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2125| accessdate = ] PBB Summary section title = summary text …   Wikipedia

  • Acne vulgaris — This article is about a skin disease commonly found during adolescence. For other acneform skin diseases, see Acne (disambiguation). Acne vulgaris Classification and external resources …   Wikipedia

  • Keratin 1 — is a member of the keratin family. It is specifically expressed in the spinous and granular layers of the epidermis with family member keratin 10. Mutations in this gene have been associated with the variants of bullous congenital ichthyosiform… …   Wikipedia

  • Keratin 4 — Identifiers Symbols KRT4; CK 4; CK4; CYK4; FLJ31692; K4 External IDs OMIM …   Wikipedia

  • Desmoplakin — PDB rendering based on 1lm5 …   Wikipedia

  • IVL — can refer to:* [http://ivl.calit2.net/wiki IVL] The Immersive Visualization Laboratory at the [http://www.calit2.net California Institute for Telecommunications and Information Technology (Calit2)] at the [http://www.ucsd.edu University of… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”