- ERCC6
Excision repair cross-complementing rodent repair deficiency, complementation group 6, also known as ERCC6, is a human
gene .cite web | title = Entrez Gene: ERCC6 excision repair cross-complementing rodent repair deficiency, complementation group 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2074| accessdate = ]PBB_Summary
section_title =
summary_text = The ERCC6 protein is a DNA-binding protein important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites.cite web | title = Entrez Gene: ERCC6 excision repair cross-complementing rodent repair deficiency, complementation group 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2074| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Cleaver JE, Thompson LH, Richardson AS, States JC |title=A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy. |journal=Hum. Mutat. |volume=14 |issue= 1 |pages= 9–22 |year= 1999 |pmid= 10447254 |doi= 10.1002/(SICI)1098-1004(1999)14:1<9::AID-HUMU2>3.0.CO;2-6 |doilabel=10.1002/(SICI)1098-1004(1999)14:19::AID-HUMU23.0.CO;2-6
*cite journal | author=Troelstra C, van Gool A, de Wit J, "et al." |title=ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. |journal=Cell |volume=71 |issue= 6 |pages= 939–53 |year= 1993 |pmid= 1339317 |doi=
*cite journal | author=Troelstra C, Landsvater RM, Wiegant J, "et al." |title=Localization of the nucleotide excision repair gene ERCC6 to human chromosome 10q11-q21. |journal=Genomics |volume=12 |issue= 4 |pages= 745–9 |year= 1992 |pmid= 1349298 |doi=
*cite journal | author=Fryns JP, Bulcke J, Verdu P, "et al." |title=Apparent late-onset Cockayne syndrome and interstitial deletion of the long arm of chromosome 10 (del(10)(q11.23q21.2)). |journal=Am. J. Med. Genet. |volume=40 |issue= 3 |pages= 343–4 |year= 1991 |pmid= 1951442 |doi= 10.1002/ajmg.1320400320
*cite journal | author=Troelstra C, Odijk H, de Wit J, "et al." |title=Molecular cloning of the human DNA excision repair gene ERCC-6. |journal=Mol. Cell. Biol. |volume=10 |issue= 11 |pages= 5806–13 |year= 1990 |pmid= 2172786 |doi=
*cite journal | author=Wang XW, Yeh H, Schaeffer L, "et al." |title=p53 modulation of TFIIH-associated nucleotide excision repair activity. |journal=Nat. Genet. |volume=10 |issue= 2 |pages= 188–95 |year= 1995 |pmid= 7663514 |doi= 10.1038/ng0695-188
*cite journal | author=Henning KA, Li L, Iyer N, "et al." |title=The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. |journal=Cell |volume=82 |issue= 4 |pages= 555–64 |year= 1995 |pmid= 7664335 |doi=
*cite journal | author=Troelstra C, Hesen W, Bootsma D, Hoeijmakers JH |title=Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group B. |journal=Nucleic Acids Res. |volume=21 |issue= 3 |pages= 419–26 |year= 1993 |pmid= 8382798 |doi=
*cite journal | author=Iyer N, Reagan MS, Wu KJ, "et al." |title=Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein. |journal=Biochemistry |volume=35 |issue= 7 |pages= 2157–67 |year= 1996 |pmid= 8652557 |doi= 10.1021/bi9524124
*cite journal | author=Selby CP, Sancar A |title=Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II. |journal=J. Biol. Chem. |volume=272 |issue= 3 |pages= 1885–90 |year= 1997 |pmid= 8999876 |doi=
*cite journal | author=Boulikas T |title=Nuclear import of DNA repair proteins. |journal=Anticancer Res. |volume=17 |issue= 2A |pages= 843–63 |year= 1997 |pmid= 9137418 |doi=
*cite journal | author=Selby CP, Sancar A |title=Cockayne syndrome group B protein enhances elongation by RNA polymerase II. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 21 |pages= 11205–9 |year= 1997 |pmid= 9326587 |doi=
*cite journal | author=Tantin D, Kansal A, Carey M |title=Recruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexes. |journal=Mol. Cell. Biol. |volume=17 |issue= 12 |pages= 6803–14 |year= 1997 |pmid= 9372911 |doi=
*cite journal | author=Mallery DL, Tanganelli B, Colella S, "et al." |title=Molecular analysis of mutations in the CSB (ERCC6) gene in patients with Cockayne syndrome. |journal=Am. J. Hum. Genet. |volume=62 |issue= 1 |pages= 77–85 |year= 1998 |pmid= 9443879 |doi=
*cite journal | author=Lindsay HD, Griffiths DJ, Edwards RJ, "et al." |title=S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. |journal=Genes Dev. |volume=12 |issue= 3 |pages= 382–95 |year= 1998 |pmid= 9450932 |doi=
*cite journal | author=Tantin D |title=RNA polymerase II elongation complexes containing the Cockayne syndrome group B protein interact with a molecular complex containing the transcription factor IIH components xeroderma pigmentosum B and p62. |journal=J. Biol. Chem. |volume=273 |issue= 43 |pages= 27794–9 |year= 1998 |pmid= 9774388 |doi=
*cite journal | author=Dianov G, Bischoff C, Sunesen M, Bohr VA |title=Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells. |journal=Nucleic Acids Res. |volume=27 |issue= 5 |pages= 1365–8 |year= 1999 |pmid= 9973627 |doi=
*cite journal | author=Colella S, Nardo T, Mallery D, "et al." |title=Alterations in the CSB gene in three Italian patients with the severe form of Cockayne syndrome (CS) but without clinical photosensitivity. |journal=Hum. Mol. Genet. |volume=8 |issue= 5 |pages= 935–41 |year= 1999 |pmid= 10196384 |doi=
*cite journal | author=Cheng L, Guan Y, Li L, "et al." |title=Expression in normal human tissues of five nucleotide excision repair genes measured simultaneously by multiplex reverse transcription-polymerase chain reaction. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=8 |issue= 9 |pages= 801–7 |year= 1999 |pmid= 10498399 |doi=PBB_Controls
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