LRP5

LRP5

Low density lipoprotein receptor-related protein 5, also known as LRP5, is a human gene.cite web | title = Entrez Gene: LRP5 low density lipoprotein receptor-related protein 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4041| accessdate = ]

PBB_Summary
section_title =
summary_text =

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=He X, Semenov M, Tamai K, Zeng X |title=LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. |journal=Development |volume=131 |issue= 8 |pages= 1663–77 |year= 2004 |pmid= 15084453 |doi= 10.1242/dev.01117
*cite journal | author=Godyna S, Liau G, Popa I, "et al." |title=Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1. |journal=J. Cell Biol. |volume=129 |issue= 5 |pages= 1403–10 |year= 1995 |pmid= 7775583 |doi=
*cite journal | author=Gong Y, Vikkula M, Boon L, "et al." |title=Osteoporosis-pseudoglioma syndrome, a disorder affecting skeletal strength and vision, is assigned to chromosome region 11q12-13. |journal=Am. J. Hum. Genet. |volume=59 |issue= 1 |pages= 146–51 |year= 1996 |pmid= 8659519 |doi=
*cite journal | author=Johnson ML, Gong G, Kimberling W, "et al." |title=Linkage of a gene causing high bone mass to human chromosome 11 (11q12-13) |journal=Am. J. Hum. Genet. |volume=60 |issue= 6 |pages= 1326–32 |year= 1997 |pmid= 9199553 |doi=
*cite journal | author=Hey PJ, Twells RC, Phillips MS, "et al." |title=Cloning of a novel member of the low-density lipoprotein receptor family. |journal=Gene |volume=216 |issue= 1 |pages= 103–11 |year= 1998 |pmid= 9714764 |doi=
*cite journal | author=Dong Y, Lathrop W, Weaver D, "et al." |title=Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity. |journal=Biochem. Biophys. Res. Commun. |volume=251 |issue= 3 |pages= 784–90 |year= 1998 |pmid= 9790987 |doi= 10.1006/bbrc.1998.9545
*cite journal | author=de Crecchio G, Simonelli F, Nunziata G, "et al." |title=Autosomal recessive familial exudative vitreoretinopathy: evidence for genetic heterogeneity. |journal=Clin. Genet. |volume=54 |issue= 4 |pages= 315–20 |year= 1999 |pmid= 9831343 |doi=
*cite journal | author=Chen D, Lathrop W, Dong Y |title=Molecular cloning of mouse Lrp7(Lr3) cDNA and chromosomal mapping of orthologous genes in mouse and human. |journal=Genomics |volume=55 |issue= 3 |pages= 314–21 |year= 1999 |pmid= 10049586 |doi= 10.1006/geno.1998.5688
*cite journal | author=Mao J, Wang J, Liu B, "et al." |title=Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. |journal=Mol. Cell |volume=7 |issue= 4 |pages= 801–9 |year= 2001 |pmid= 11336703 |doi=
*cite journal | author=Twells RC, Metzker ML, Brown SD, "et al." |title=The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13. |journal=Genomics |volume=72 |issue= 3 |pages= 231–42 |year= 2001 |pmid= 11401438 |doi= 10.1006/geno.2000.6492
*cite journal | author=Semënov MV, Tamai K, Brott BK, "et al." |title=Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. |journal=Curr. Biol. |volume=11 |issue= 12 |pages= 951–61 |year= 2001 |pmid= 11448771 |doi=
*cite journal | author=Zorn AM |title=Wnt signalling: antagonistic Dickkopfs. |journal=Curr. Biol. |volume=11 |issue= 15 |pages= R592–5 |year= 2001 |pmid= 11516963 |doi=
*cite journal | author=Gong Y, Slee RB, Fukai N, "et al." |title=LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. |journal=Cell |volume=107 |issue= 4 |pages= 513–23 |year= 2002 |pmid= 11719191 |doi=
*cite journal | author=Little RD, Carulli JP, Del Mastro RG, "et al." |title=A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. |journal=Am. J. Hum. Genet. |volume=70 |issue= 1 |pages= 11–9 |year= 2002 |pmid= 11741193 |doi=
*cite journal | author=Okubo M, Horinishi A, Kim DH, "et al." |title=Seven novel sequence variants in the human low density lipoprotein receptor related protein 5 (LRP5) gene. |journal=Hum. Mutat. |volume=19 |issue= 2 |pages= 186 |year= 2002 |pmid= 11793484 |doi= 10.1002/humu.9012
*cite journal | author=Boyden LM, Mao J, Belsky J, "et al." |title=High bone density due to a mutation in LDL-receptor-related protein 5. |journal=N. Engl. J. Med. |volume=346 |issue= 20 |pages= 1513–21 |year= 2002 |pmid= 12015390 |doi= 10.1056/NEJMoa013444
*cite journal | author=Van Hul E, Gram J, Bollerslev J, "et al." |title=Localization of the gene causing autosomal dominant osteopetrosis type I to chromosome 11q12-13. |journal=J. Bone Miner. Res. |volume=17 |issue= 6 |pages= 1111–7 |year= 2002 |pmid= 12054167 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Fujino T, Asaba H, Kang MJ, "et al." |title=Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 1 |pages= 229–34 |year= 2003 |pmid= 12509515 |doi= 10.1073/pnas.0133792100
*cite journal | author=Van Wesenbeeck L, Cleiren E, Gram J, "et al." |title=Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density. |journal=Am. J. Hum. Genet. |volume=72 |issue= 3 |pages= 763–71 |year= 2003 |pmid= 12579474 |doi=

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Sclerostin — Sclerostin, the product of the SOST gene, was originally believed to be a non classical Bone morphogenetic protein (BMP) antagonist. More recently Sclerostin has been identified as binding to LRP5/6 receptors and activating the Wnt signalling… …   Wikipedia

  • Co-receptor — A co receptor is a cell surface receptor that binds a signalling molecule in addition to a primary receptor in order to facilitate ligand recognition and initiate biological processes, such as entry of a pathogen into a host cell. Contents 1 Co… …   Wikipedia

  • Сигнальный путь Wnt — Сигнальный путь Wnt  один из сигнальных путей клетки животных, регулирующий эмбриогенез, дифференцировку тканей и развитие раковых опухолей[1][2]. Содержание 1 Открытие 2 Структур …   Википедия

  • Osteopetrosis — (Malignant) Classification and external resources X ray of the pelvis of a patient with osteopetrosis, adult onset form (Albers Schonberg disease). Note the dense bones. ICD …   Wikipedia

  • FZD4 — Frizzled homolog 4 (Drosophila), also known as FZD4, is a human gene.cite web | title = Entrez Gene: FZD4 frizzled homolog 4 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=8322| accessdate = ] …   Wikipedia

  • Genetic disorder — For a non technical introduction to the topic, see Introduction to genetics. Genetic disorder Classification and external resources MeSH D030342 A genetic disorder is an illness caused by abnormalities in genes or …   Wikipedia

  • Lipid — Structures of some common lipids. At the top are oleic acid[1] and cholesterol.[2] The middle structure is a triglyceride composed of oleoyl, stearoyl, and palmitoyl chains at …   Wikipedia

  • Neurotransmitter — For an introduction to concepts and terminology used in this article, see Chemical synapse. Structure of a typical chemical synapse Postsynaptic density Voltage gated Ca++ c …   Wikipedia

  • Achondroplasia — Classification and external resources Jason Acuña, alias Wee Man , a star of Jackass …   Wikipedia

  • Donohue syndrome — Classification and external resources insulin receptor OMIM 246200 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”