S100A9

S100 calcium binding protein A9, also known as S100A9, is a human gene.

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis.cite web | title = Entrez Gene: S100A9 S100 calcium binding protein A9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6280| accessdate = ]

ee also

* S-100 protein

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Schäfer BW, Heizmann CW |title=The S100 family of EF-hand calcium-binding proteins: functions and pathology. |journal=Trends Biochem. Sci. |volume=21 |issue= 4 |pages= 134–40 |year= 1996 |pmid= 8701470 |doi=
*cite journal | author=Kerkhoff C, Klempt M, Sorg C |title=Novel insights into structure and function of MRP8 (S100A8) and MRP14 (S100A9). |journal=Biochim. Biophys. Acta |volume=1448 |issue= 2 |pages= 200–11 |year= 1999 |pmid= 9920411 |doi=
*cite journal | author=Nacken W, Roth J, Sorg C, Kerkhoff C |title=S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity. |journal=Microsc. Res. Tech. |volume=60 |issue= 6 |pages= 569–80 |year= 2003 |pmid= 12645005 |doi= 10.1002/jemt.10299
*cite journal | author=Rasmussen HH, van Damme J, Puype M, "et al." |title=Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. |journal=Electrophoresis |volume=13 |issue= 12 |pages= 960–9 |year= 1993 |pmid= 1286667 |doi=10.1002/elps.11501301199
*cite journal | author=Longbottom D, Sallenave JM, van Heyningen V |title=Subunit structure of calgranulins A and B obtained from sputum, plasma, granulocytes and cultured epithelial cells. |journal=Biochim. Biophys. Acta |volume=1120 |issue= 2 |pages= 215–22 |year= 1992 |pmid= 1562590 |doi=
*cite journal | author=Dorin JR, Emslie E, van Heyningen V |title=Related calcium-binding proteins map to the same subregion of chromosome 1q and to an extended region of synteny on mouse chromosome 3. |journal=Genomics |volume=8 |issue= 3 |pages= 420–6 |year= 1991 |pmid= 2149559 |doi=10.1016/0888-7543(90)90027-R
*cite journal | author=Edgeworth J, Freemont P, Hogg N |title=Ionomycin-regulated phosphorylation of the myeloid calcium-binding protein p14. |journal=Nature |volume=342 |issue= 6246 |pages= 189–92 |year= 1989 |pmid= 2478889 |doi= 10.1038/342189a0
*cite journal | author=Murao S, Collart FR, Huberman E |title=A protein containing the cystic fibrosis antigen is an inhibitor of protein kinases. |journal=J. Biol. Chem. |volume=264 |issue= 14 |pages= 8356–60 |year= 1989 |pmid= 2656677 |doi=
*cite journal | author=Odink K, Cerletti N, Brüggen J, "et al." |title=Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. |journal=Nature |volume=330 |issue= 6143 |pages= 80–2 |year= 1987 |pmid= 3313057 |doi= 10.1038/330080a0
*cite journal | author=Lagasse E, Clerc RG |title=Cloning and expression of two human genes encoding calcium-binding proteins that are regulated during myeloid differentiation. |journal=Mol. Cell. Biol. |volume=8 |issue= 6 |pages= 2402–10 |year= 1988 |pmid= 3405210 |doi=
*cite journal | author=Schäfer BW, Wicki R, Engelkamp D, "et al." |title=Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. |journal=Genomics |volume=25 |issue= 3 |pages= 638–43 |year= 1995 |pmid= 7759097 |doi=10.1016/0888-7543(95)80005-7
*cite journal | author=Engelkamp D, Schäfer BW, Mattei MG, "et al." |title=Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 14 |pages= 6547–51 |year= 1993 |pmid= 8341667 |doi=10.1073/pnas.90.14.6547
*cite journal | author=Roth J, Burwinkel F, van den Bos C, "et al." |title=MRP8 and MRP14, S-100-like proteins associated with myeloid differentiation, are translocated to plasma membrane and intermediate filaments in a calcium-dependent manner. |journal=Blood |volume=82 |issue= 6 |pages= 1875–83 |year= 1993 |pmid= 8400238 |doi=
*cite journal | author=Miyasaki KT, Bodeau AL, Murthy AR, Lehrer RI |title=In vitro antimicrobial activity of the human neutrophil cytosolic S-100 protein complex, calprotectin, against Capnocytophaga sputigena. |journal=J. Dent. Res. |volume=72 |issue= 2 |pages= 517–23 |year= 1993 |pmid= 8423249 |doi=
*cite journal | author=Newton RA, Hogg N |title=The human S100 protein MRP-14 is a novel activator of the beta 2 integrin Mac-1 on neutrophils. |journal=J. Immunol. |volume=160 |issue= 3 |pages= 1427–35 |year= 1998 |pmid= 9570563 |doi=
*cite journal | author=Vogl T, Pröpper C, Hartmann M, "et al." |title=S100A12 is expressed exclusively by granulocytes and acts independently from MRP8 and MRP14. |journal=J. Biol. Chem. |volume=274 |issue= 36 |pages= 25291–6 |year= 1999 |pmid= 10464253 |doi=10.1074/jbc.274.36.25291
*cite journal | author=Kerkhoff C, Klempt M, Kaever V, Sorg C |title=The two calcium-binding proteins, S100A8 and S100A9, are involved in the metabolism of arachidonic acid in human neutrophils. |journal=J. Biol. Chem. |volume=274 |issue= 46 |pages= 32672–9 |year= 2000 |pmid= 10551823 |doi=10.1074/jbc.274.46.32672
*cite journal | author=Stulík J, Koupilova K, Osterreicher J, "et al." |title=Protein abundance alterations in matched sets of macroscopically normal colon mucosa and colorectal carcinoma. |journal=Electrophoresis |volume=20 |issue= 18 |pages= 3638–46 |year= 2000 |pmid= 10612291 |doi= 10.1002/(SICI)1522-2683(19991201)20:18<3638::AID-ELPS3638>3.0.CO;2-W

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