Griffithsin

Griffithsin

Griffithsin, is a protein isolated from the red algae Griffithsia. It has a 121-amino acid sequence. [cite journal |author=Mori T, O'Keefe BR, Sowder RC, "et al" |title=Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp |journal=J. Biol. Chem. |volume=280 |issue=10 |pages=9345–53 |year=2005 |pmid=15613479 |doi=10.1074/jbc.M411122200 |url=http://www.jbc.org/cgi/pmidlookup?view=long&pmid=15613479] It has been shown in vitro to be a highly potent HIV entry inhibitor. It is currently being investigated as a potential microbicide for use in the prevention of the transmission of HIV. [cite journal |author=Emau P, Tian B, O'keefe BR, "et al" |title=Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide |journal=J. Med. Primatol. |volume=36 |issue=4-5 |pages=244–53 |year=2007 |pmid=17669213 |doi=10.1111/j.1600-0684.2007.00242.x |url=http://www.blackwell-synergy.com/openurl?genre=article&sid=nlm:pubmed&issn=0047-2565&date=2007&volume=36&issue=4-5&spage=244]


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • griffithsin — noun A protein, isolated from the red alga Griffithsia, that may have some use as a microbicide …   Wiktionary

  • Entry inhibitor — Entry inhibitors, also known as fusion inhibitors, are a class of antiretroviral drugs, used in combination therapy for the treatment of HIV infection. This class of drugs interferes with the binding, fusion and entry of an HIV virion to a human… …   Wikipedia

  • Inhibidor de fusión — Inhibidor de entrada, también conocido como inhibidor de fusión, es un tipo de antirretroviral usado en la terapia de combinación para el tratamiento por infección del VIH. Este tipo de medicamento interfiere en la entrada del virión VIH a la… …   Wikipedia Español

  • Zidovudine — AZT redirects here. For other uses, see AZT (disambiguation). Zidovudine Systematic (IUPAC) name …   Wikipedia

  • Antiretroviral drug — HAART redirects here. For UK estate agency Haart, see Spicerhaart. Antiretroviral drugs are medications for the treatment of infection by retroviruses, primarily HIV. When several such drugs, typically three or four, are taken in combination, the …   Wikipedia

  • Didanosine — Systematic (IUPAC) name 9 [(2R,5S) 5 (hydroxymethyl)oxolan 2 yl] 6,9 dihydro 3H purin 6 one Clinical data AHFS/Drugs.c …   Wikipedia

  • Zalcitabine — Systematic (IUPAC) name 4 amino 1 ((2R,5S) 5 (hydroxymethyl)tetrahydrofuran 2 yl)pyrimidin 2(1H) one Clinical data AHFS/Drugs.com …   Wikipedia

  • Stavudine — Systematic (IUPAC) name 1 ((2R,5S) 5 (hydroxymethyl) 2,5 dihydrofuran 2 yl) 5 methylpyrimidine 2,4(1H,3H) dione Clinical data AHFS/Drugs.com …   Wikipedia

  • Emtricitabine — Systematic (IUPAC) name 4 amino 5 fluoro 1 [(2S,5R) 2 (hydroxymethyl) 1,3 oxathiolan 5 yl] 1,2 dihydropyrimidin 2 one Clinical data …   Wikipedia

  • Ritonavir — Systematic (IUPAC) name 1,3 thiazol 5 ylmethyl N [(2S,3S,5S) 3 hydroxy 5 [(2S) 3 methyl 2 {[methyl({[2 (propan 2 yl) 1,3 thiazol 4 yl]methyl})carbamoyl]amino}butanamido] 1,6 diphenylhexan 2 yl]carbamate …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”