- Glycolipid 2-alpha-mannosyltransferase
In enzymology, a glycolipid 2-alpha-mannosyltransferase (EC number|22.214.171.124) is an enzyme that catalyzes the chemical reaction in which an alpha-D-mannosyl residue is transferred from GDP-mannose to lipid-linked oligosaccharide, being attached by an alpha-1,2-D-mannosyl-D-mannose bond.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase. Other names in common use include guanosine diphosphomannose-oligosaccharide-lipid, mannosyltransferase, GDP-mannose-oligosaccharide-lipid mannosyltransferase, and oligosaccharide-lipid mannosyltransferase.
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1S4N, PDB link|1S4O, and PDB link|1S4P.
::"The CAS registry number for this enzyme class is CAS registry|74506-43-7."
Gene Ontology (GO) codes
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