- Pyruvate, water dikinase
In
enzymology , a pyruvate, water dikinase (EC number|2.7.9.2) is anenzyme that catalyzes thechemical reaction :ATP + pyruvate + H2O AMP + phosphoenolpyruvate + phosphate
The 3 substrates of this enzyme are ATP,
pyruvate , and H2O, whereas its 3 products are AMP,phosphoenolpyruvate , andphosphate .This enzyme belongs to the family of
transferase s, specifically those transferring phosphorus-containing groups (phosphotransferase s) with paired acceptors. The systematic name of this enzyme class is ATP:pyruvate, water phosphotransferase. Other names in common use include phosphoenolpyruvate synthase, pyruvate-water dikinase (phosphorylating), PEP synthetase, phosphoenolpyruvate synthase, phoephoenolpyruvate synthetase, phosphoenolpyruvic synthase, and phosphopyruvate synthetase. This enzyme participates inpyruvate metabolism andreductive carboxylate cycle (co2 fixation) . It employs one cofactor,manganese .tructural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2OLS.
References
*
*
*
*External links
::"The
CAS registry number for this enzyme class is CAS registry|9013-09-6."Gene Ontology (GO) codes
Wikimedia Foundation. 2010.