Phosphatidate cytidylyltransferase
- Phosphatidate cytidylyltransferase
In enzymology, a phosphatidate cytidylyltransferase (EC number|2.7.7.41) is an enzyme that catalyzes the chemical reaction
:CTP + phosphatidate diphosphate + CDP-diacylglycerol
Thus, the two substrates of this enzyme are CTP and phosphatidate, whereas its two products are diphosphate and CDP-diacylglycerol.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:phosphatidate cytidylyltransferase. Other names in common use include CDP diglyceride pyrophosphorylase, CDP-diacylglycerol synthase, CDP-diacylglyceride synthetase, cytidine diphosphoglyceride pyrophosphorylase, phosphatidate cytidyltransferase, phosphatidic acid cytidylyltransferase, CTP:1,2-diacylglycerophosphate-cytidyl transferase, CTP-diacylglycerol synthetase, DAG synthetase, and CDP-DG. This enzyme participates in glycerophospholipid metabolism and phosphatidylinositol signaling system.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|9067-83-8."
Gene Ontology (GO) codes
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phosphatidate cytidylyltransferase — phos·pha·ti·date cy·ti·dyl·yl·trans·fer·ase (fos″fə tiґdāt si″tĭ dil″əl transґfər ās) [EC 2.7.7.41] an enzyme of the transferase class that catalyzes the synthesis of CDPdiacylglycerol from CTP and… … Medical dictionary
CDS2 — CDP diacylglycerol synthase (phosphatidate cytidylyltransferase) 2, also known as CDS2, is a human gene.cite web | title = Entrez Gene: CDS2 CDP diacylglycerol synthase (phosphatidate cytidylyltransferase) 2| url =… … Wikipedia
CDS1 (gene) — CDP diacylglycerol synthase (phosphatidate cytidylyltransferase) 1, also known as CDS1, is a human gene.cite web | title = Entrez Gene: CDS1 CDP diacylglycerol synthase (phosphatidate cytidylyltransferase) 1| url =… … Wikipedia
List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… … Wikipedia
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Diacylglycerol kinase — catalytic domain Identifiers Symbol DAGK cat Pfam PF00781 Pfam clan … Wikipedia
