Glucuronate-1-phosphate uridylyltransferase

In enzymology, a glucuronate-1-phosphate uridylyltransferase (EC number|2.7.7.44) is an enzyme that catalyzes the chemical reaction

:UTP + 1-phospho-alpha-D-glucuronate $ightleftharpoons$ diphosphate + UDP-glucuronate

Thus, the two substrates of this enzyme are UTP and 1-phospho-alpha-D-glucuronate, whereas its two products are diphosphate and UDP-glucuronate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:1-phospho-alpha-D-glucuronate uridylyltransferase. Other names in common use include UDP-glucuronate pyrophosphorylase, UDP-D-glucuronic acid pyrophosphorylase, UDP-glucuronic acid pyrophosphorylase, and uridine diphosphoglucuronic pyrophosphorylase. This enzyme participates in pentose and glucuronate interconversions and ascorbate and aldarate metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|52228-05-4."

Gene Ontology (GO) codes