Glucose-1-phosphate adenylyltransferase

In enzymology, a glucose-1-phosphate adenylyltransferase (EC number|2.7.7.27) is an enzyme that catalyzes the chemical reaction

:ATP + alpha-D-glucose 1-phosphate $ightleftharpoons$ diphosphate + ADP-glucose

Thus, the two substrates of this enzyme are ATP and alpha-D-glucose 1-phosphate, whereas its two products are diphosphate and ADP-glucose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:alpha-D-glucose-1-phosphate adenylyltransferase. Other names in common use include ADP glucose pyrophosphorylase, glucose 1-phosphate adenylyltransferase, adenosine diphosphate glucose pyrophosphorylase, adenosine diphosphoglucose pyrophosphorylase, ADP-glucose pyrophosphorylase, ADP-glucose synthase, ADP-glucose synthetase, ADPG pyrophosphorylase, and ADP:alpha-D-glucose-1-phosphate adenylyltransferase. This enzyme participates in starch and sucrose metabolism.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1YP2, PDB link|1YP3, and PDB link|1YP4.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9027-71-8."

Gene Ontology (GO) codes