Starch synthase

In enzymology, a starch synthase (EC number|2.4.1.21) is an enzyme that catalyzes the chemical reaction

:ADP-glucose + (1,4-alpha-D-glucosyl)n $ightleftharpoons$ ADP + (1,4-alpha-D-glucosyl)n⁺1

Thus, the two substrates of this enzyme are ADP-glucose and (1,4-alpha-D-glucosyl)n, whereas its two products are ADP and (1,4-alpha-D-glucosyl)n+1.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase. Other names in common use include ADP-glucose-starch glucosyltransferase, adenosine diphosphate glucose-starch glucosyltransferase, adenosine diphosphoglucose-starch glucosyltransferase, ADP-glucose starch synthase, ADP-glucose synthase, ADP-glucose transglucosylase, ADP-glucose-starch glucosyltransferase, ADPG starch synthetase, ADPG-starch glucosyltransferase, and starch synthetase. This enzyme participates in starch and sucrose metabolism.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1RZU, PDB link|1RZV, PDB link|2BFW, and PDB link|2BIS.

References

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* Whelan, W.J. and Schultz, J. (Eds.), Miami Winter Symposia, vol. 1, North Holland, Utrecht, 1970, p. 122-138.

External links

::"The CAS registry number for this enzyme class is CAS registry|9030-10-8."

Gene Ontology (GO) codes