Phosphatidylinositol N-acetylglucosaminyltransferase

In enzymology, a phosphatidylinositol N-acetylglucosaminyltransferase (EC number|2.4.1.198) is an enzyme that catalyzes the chemical reaction

:UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol $ightleftharpoons$ UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol

Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and 1-phosphatidyl-1D-myo-inositol, whereas its two products are UDP and 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:1-phosphatidyl-1D-myo-inositol 6-(N-acetyl-alpha-D-glucosaminyl)transferase. Other names in common use include UDP-N-acetyl-D-glucosamine:phosphatidylinositol, N-acetyl-D-glucosaminyltransferase, uridine diphosphoacetylglucosamine, and alpha1,6-acetyl-D-glucosaminyltransferase. This enzyme participates in 3 metabolic pathways: glycosylphosphatidylinositol(gpi)-anchor, , and glycan structures - biosynthesis 2.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|144388-35-2."

Gene Ontology (GO) codes