N-acylsphingosine galactosyltransferase

N-acylsphingosine galactosyltransferase
Identifiers
EC number	2.4.1.47
CAS number	37277-56-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a N-acylsphingosine galactosyltransferase (EC 2.4.1.47) is an enzyme that catalyzes the chemical reaction

UDP-galactose + N-acylsphingosine $\rightleftharpoons$ UDP + D-galactosylceramide

Thus, the two substrates of this enzyme are UDP-galactose and N-acylsphingosine, whereas its two products are UDP and D-galactosylceramide.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:N-acylsphingosine D-galactosyltransferase. Other names in common use include UDP galactose-N-acylsphingosine galactosyltransferase, and uridine diphosphogalactose-acylsphingosine galactosyltransferase. This enzyme participates in sphingolipid metabolism.

References

• Fujino Y, Nakano M (1969). "Enzymic synthesis of cerebroside from ceramide and uridine diphosphate galactose". Biochem. J. 113 (3): 573–5. PMC 1184705. PMID 5807218. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1184705. 

This enzyme-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Enzyme stubs EC 2.4.1 Enzymes of unknown structure Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Murder, Inc. trials José Makila Sumanda Look at other dictionaries: Ganglioside galactosyltransferase — In enzymology, a ganglioside galactosyltransferase (EC number|2.4.1.62) is an enzyme that catalyzes the chemical reaction:UDP galactose + N acetyl D galactosaminyl (N acetylneuraminyl) D galactosyl 1,4 beta D glucosyl N acylsphingosine… …   Wikipedia List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”