- Antimicrobial peptide resistance and lipid A acylation protein family
Pfam_box
Symbol = PagP
Name = Antimicrobial peptide resistance and lipid A acylation protein PagP
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Pfam= PF07017
InterPro= IPR009746
SMART=
Prosite =
SCOP =
TCDB =
OPM family= 26
OPM protein= 1thq
PDB=PDB3|1mm5A:36-183 PDB3|1mm4A:36-183 PDB3|1thqA:36-183Antimicrobial peptide resistance and lipid A acylation protein PagP is a family of several bacterial
antimicrobial peptide resistance andlipid A acylation (PagP) proteins. The bacterial outer membrane enzyme PagP transfers a palmitate chain from a phospholipid to lipid A. In a number of pathogenicGram-negative bacteria , PagP confers resistance to certain cationic antimicrobial peptides produced during the hostinnate immune response .References
* [1] . Solution structure and dynamics of the outer membrane enzyme PagP by NMR. Hwang PM, Choy WY, Lo EI, Chen L, Forman-Kay JD, Raetz CR, Prive GG, Bishop RE, Kay LE; Proc Natl Acad Sci U S A 2002;99:13560-13565. PMID|12357033
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