CAMK2G

Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma, also known as CAMK2G, is a human gene.

PBB_Summary
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summary_text = The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Six alternatively spliced variants that encode six different isoforms have been characterized to date. Additional alternative splice variants that encode different isoforms have been described, but their full-length nature has not been determined. [cite web | title = Entrez Gene: CAMK2G calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=818| accessdate = ]

ee also

Ca2+/calmodulin-dependent protein kinase

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hook SS, Means AR |title=Ca(2+)/CaM-dependent kinases: from activation to function. |journal=Annu. Rev. Pharmacol. Toxicol. |volume=41 |issue= |pages= 471–505 |year= 2001 |pmid= 11264466 |doi= 10.1146/annurev.pharmtox.41.1.471
*cite journal | author=Yamamoto H |title= [Molecular mechanisms of the intracellular localizations of Ca2+/calmodulin-dependent protein kinase II isoforms, and their physiological functions] |journal=Tanpakushitsu Kakusan Koso |volume=47 |issue= 3 |pages= 241–7 |year= 2002 |pmid= 11889801 |doi=
*cite journal | author=Countaway JL, Nairn AC, Davis RJ |title=Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase. |journal=J. Biol. Chem. |volume=267 |issue= 2 |pages= 1129–40 |year= 1992 |pmid= 1309762 |doi=
*cite journal | author=Ikebe M, Reardon S |title=Phosphorylation of smooth myosin light chain kinase by smooth muscle Ca2+/calmodulin-dependent multifunctional protein kinase. |journal=J. Biol. Chem. |volume=265 |issue= 16 |pages= 8975–8 |year= 1990 |pmid= 2160950 |doi=
*cite journal | author=Czernik AJ, Pang DT, Greengard P |title=Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin I. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 21 |pages= 7518–22 |year= 1987 |pmid= 3118371 |doi=
*cite journal | author=Vulliet PR, Woodgett JR, Cohen P |title=Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase. |journal=J. Biol. Chem. |volume=259 |issue= 22 |pages= 13680–3 |year= 1984 |pmid= 6150037 |doi=
*cite journal | author=Wen Z, Zhong Z, Darnell JE |title=Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. |journal=Cell |volume=82 |issue= 2 |pages= 241–50 |year= 1995 |pmid= 7543024 |doi=
*cite journal | author=Kwiatkowski AP, McGill JM |title=Human biliary epithelial cell line Mz-ChA-1 expresses new isoforms of calmodulin-dependent protein kinase II. |journal=Gastroenterology |volume=109 |issue= 4 |pages= 1316–23 |year= 1995 |pmid= 7557101 |doi=
*cite journal | author=Shuai K, Stark GR, Kerr IM, Darnell JE |title=A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. |journal=Science |volume=261 |issue= 5129 |pages= 1744–6 |year= 1993 |pmid= 7690989 |doi=
*cite journal | author=Zhu J, Reynet C, Caldwell JS, Kahn CR |title=Characterization of Rad, a new member of Ras/GTPase superfamily, and its regulation by a unique GTPase-activating protein (GAP)-like activity. |journal=J. Biol. Chem. |volume=270 |issue= 9 |pages= 4805–12 |year= 1995 |pmid= 7876254 |doi=
*cite journal | author=Yakel JL, Vissavajjhala P, Derkach VA, "et al." |title=Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 5 |pages= 1376–80 |year= 1995 |pmid= 7877986 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Li X, Nghiem P, Schulman H, Francke U |title=Localization of the CAMKG gene encoding gamma isoforms of multifunctional calcium/calmodulin-dependent protein kinase (CaM kinase) to human chromosome 10 band q22 and mouse chromosome 14. |journal=Cytogenet. Cell Genet. |volume=66 |issue= 2 |pages= 113–6 |year= 1994 |pmid= 8287681 |doi=
*cite journal | author=Suko J, Maurer-Fogy I, Plank B, "et al." |title=Phosphorylation of serine 2843 in ryanodine receptor-calcium release channel of skeletal muscle by cAMP-, cGMP- and CaM-dependent protein kinase. |journal=Biochim. Biophys. Acta |volume=1175 |issue= 2 |pages= 193–206 |year= 1993 |pmid= 8380342 |doi=
*cite journal | author=de Groot RP, den Hertog J, Vandenheede JR, "et al." |title=Multiple and cooperative phosphorylation events regulate the CREM activator function. |journal=EMBO J. |volume=12 |issue= 10 |pages= 3903–11 |year= 1993 |pmid= 8404858 |doi=
*cite journal | author=Nghiem P, Saati SM, Martens CL, "et al." |title=Cloning and analysis of two new isoforms of multifunctional Ca2+/calmodulin-dependent protein kinase. Expression in multiple human tissues. |journal=J. Biol. Chem. |volume=268 |issue= 8 |pages= 5471–9 |year= 1993 |pmid= 8449910 |doi=
*cite journal | author=Shimomura A, Ogawa Y, Kitani T, "et al." |title=Calmodulin-dependent protein kinase II potentiates transcriptional activation through activating transcription factor 1 but not cAMP response element-binding protein. |journal=J. Biol. Chem. |volume=271 |issue= 30 |pages= 17957–60 |year= 1996 |pmid= 8663317 |doi=
*cite journal | author=Wei J, Wayman G, Storm DR |title=Phosphorylation and inhibition of type III adenylyl cyclase by calmodulin-dependent protein kinase II in vivo. |journal=J. Biol. Chem. |volume=271 |issue= 39 |pages= 24231–5 |year= 1996 |pmid= 8798667 |doi=
*cite journal | author=Tombes RM, Krystal GW |title=Identification of novel human tumor cell-specific CaMK-II variants. |journal=Biochim. Biophys. Acta |volume=1355 |issue= 3 |pages= 281–92 |year= 1997 |pmid= 9060999 |doi=
*cite journal | author=Moyers JS, Bilan PJ, Zhu J, Kahn CR |title=Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II. |journal=J. Biol. Chem. |volume=272 |issue= 18 |pages= 11832–9 |year= 1997 |pmid= 9115241 |doi=

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