Snake toxins

Snake toxins

Pfam_box
Symbol = Toxin_1
Name = Snake toxin


width =
caption =
Pfam= PF00087
InterPro= IPR003571
SMART=
PROSITE = PDOC00245
SCOP = 2ctx
TCDB =
OPM family= 55
OPM protein= 1txa
PDB=PDB3|1ntx :1-60 PDB3|2era :22-83 PDB3|3eraB:22-83PDB3|1qke :22-83 PDB3|1qkdA:22-83 PDB3|5ebx :22-83PDB3|1fra :22-83 PDB3|3ebx :22-83 PDB3|6ebxA:22-83PDB3|1nxb :22-83 PDB3|1era :22-83 PDB3|1nea :1-61PDB3|1iq9A:1-61 PDB3|1lnkA:1-61 PDB3|1v6pA:22-83PDB3|1coe :22-83 PDB3|1cod :22-83 PDB3|1g6mA:1-62PDB3|1y5tA:22-82 PDB3|1y5sA:22-82 PDB3|1vb0A:22-82PDB3|1onjA:22-82 PDB3|1nor :1-61 PDB3|1je9A:1-61PDB3|1txa :1-65 PDB3|1txb :1-65 PDB3|2ctx :1-64PDB3|1yi5F:1-64 PDB3|1lxgA:1-64 PDB3|1lxhA:1-64PDB3|1ctx :1-64 PDB3|2abxA:22-87 PDB3|1idiA:22-88PDB3|1jbdA:22-88 PDB3|1ljzA:22-88 PDB3|1haaA:22-88PDB3|1l4wA:22-88 PDB3|1idlA:22-88 PDB3|1lk1F:22-88PDB3|1bxpA:22-88 PDB3|1ikcA:22-88 PDB3|1hajA:22-88PDB3|1idhA:22-88 PDB3|1kfhA:22-88 PDB3|1abtA:22-88PDB3|1hoyA:22-88 PDB3|1rgjA:22-88 PDB3|1idgA:22-88PDB3|2btxA:22-88 PDB3|1kc4A:22-88 PDB3|1kl8A:22-88PDB3|1ik8A:22-88 PDB3|1ntn :1-66 PDB3|1w6bA:1-66PDB3|1lsi :22-85 PDB3|1kbaB:22-87 PDB3|2nbtA:22-87PDB3|1jgkA:25-87 PDB3|1lq3A:1-65 PDB3|1xw1A:1-65PDB3|1y5pA:1-65 PDB3|1y5qA:1-65 PDB3|1lmgA:1-65PDB3|1xw0A:1-65 PDB3|1ln9A:1-65 PDB3|1y6cA:22-86PDB3|1y68A:22-86 PDB3|1xvzA:1-62 PDB3|1ln7A:1-62PDB3|1ff4A:22-86 PDB3|1ug4A:22-81 PDB3|1cb9A:1-60PDB3|1ccqA:1-60 PDB3|1ffjA:1-60 PDB3|1i02A:22-81PDB3|1xt3B:22-81 PDB3|1h0jA:22-81 PDB3|2crt :22-81PDB3|2crs :22-81 PDB3|2cdx :22-81 PDB3|1rl5A:1-60PDB3|1chvS:1-60 PDB3|1kbt :22-81 PDB3|1kbs :22-81PDB3|1cre :22-81 PDB3|1crf :22-81 PDB3|1cdtA:1-60PDB3|2ccx :1-60 PDB3|1cxo :1-60 PDB3|1tgxA:1-60PDB3|1cxn :1-60 PDB3|1kxiB:22-83 PDB3|1cvo :22-83PDB3|1tfs :1-60 PDB3|1drs :1-59 PDB3|1vylA:1-57PDB3|1ijcA:1-63 PDB3|1f94A:1-63

Snake toxin is a family of venomous protein neurotoxins and cytotoxins. Most of these toxins act by binding to the nicotinic acetylcholine receptors in the postsynaptic membrane of skeletal muscles and prevent the binding of acetylcholine, thereby blocking the excitation of muscles. Their structure is small, disulfide-rich, and nearly all beta-sheet.

ubfamilies

*Snake cytotoxin InterPro|IPR003572

ee also

*Snake venom

References

* [1] . Classification of elapid snake neurotoxins and cytotoxins according to chain length: evolutionary implications. Dufton MJ; J Mol Evol 1984;20:128-134. PMID|6433031
* [2] . Finding flexible patterns in unaligned protein sequences. Jonassen I, Collins JF, Higgins DG; Protein Sci 1995;4:1587-1595. PMID|8520485


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