Polysialic-acid O-acetyltransferase

In enzymology, a polysialic-acid O-acetyltransferase (EC number|2.3.1.136) is an enzyme that catalyzes the chemical reaction

:acetyl-CoA + an alpha-2,8-linked polymer of sialic acid $ightleftharpoons$ CoA + polysialic acid acetylated on O-7 or O-9

Thus, the two substrates of this enzyme are acetyl-CoA and alpha-2,8-linked polymer of sialic acid, whereas its 3 products are CoA, polysialic acid acetylated on O-7, and polysialic acid acetylated on O-9.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:polysialic-acid O-acetyltransferase. Other names in common use include lecithin:retinol acyltransferase, lecithin-retinol acyltransferase, retinyl ester synthase, LRAT, and lecithin retinol acyl transferase.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|116412-21-6."

Gene Ontology (GO) codes