Glycylpeptide N-tetradecanoyltransferase

In enzymology, a glycylpeptide N-tetradecanoyltransferase (EC number|2.3.1.97) is an enzyme that catalyzes the chemical reaction

:tetradecanoyl-CoA + glycylpeptide $ightleftharpoons$ CoA + N-tetradecanoylglycylpeptide

Thus, the two substrates of this enzyme are tetradecanoyl-CoA and glycylpeptide, whereas its two products are CoA and N-tetradecanoylglycylpeptide.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase. Other names in common use include peptide N-myristoyltransferase, myristoyl-CoA-protein N-myristoyltransferase, myristoyl-coenzyme A:protein N-myristoyl transferase, myristoylating enzymes, and protein N-myristoyltransferase.

tructural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1IIC, PDB link|1IID, PDB link|1IYK, PDB link|1IYL, PDB link|1RXT, PDB link|2NMT, PDB link|2P6E, PDB link|2P6F, and PDB link|2P6G.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|110071-61-9."

Gene Ontology (GO) codes