- Glucosamine-phosphate N-acetyltransferase
In
enzymology , a glucosamine-phosphate N-acetyltransferase (EC number|2.3.1.4) is anenzyme that catalyzes thechemical reaction :acetyl-CoA + D-glucosamine 6-phosphate CoA + N-acetyl-D-glucosamine 6-phosphate
Thus, the two substrates of this enzyme are
acetyl-CoA andD-glucosamine 6-phosphate , whereas its two products are CoA andN-acetyl-D-glucosamine 6-phosphate .This enzyme belongs to the family of
transferase s, specifically thoseacyltransferase s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase. Other names in common use include phosphoglucosamine transacetylase, phosphoglucosamine acetylase, glucosamine-6-phosphate acetylase, D-glucosamine-6-P N-acetyltransferase, aminodeoxyglucosephosphate acetyltransferase, glucosamine 6-phosphate acetylase, glucosamine 6-phosphate N-acetyltransferase, N-acetylglucosamine-6-phosphate synthase, phosphoglucosamine N-acetylase, glucosamine-phosphate N-acetyltransferase, and glucosamine-6-phosphate N-acetyltransferase. This enzyme participates inglutamate metabolism andaminosugars metabolism .tructural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1I12, PDB link|1I1D, PDB link|1I21, PDB link|2HUZ, and PDB link|2O28.
References
*
*
*
*External links
::"The
CAS registry number for this enzyme class is CAS registry|9031-91-8."Gene Ontology (GO) codes
Wikimedia Foundation. 2010.