3-oxoadipyl-CoA thiolase

In enzymology, a 3-oxoadipyl-CoA thiolase (EC number|2.3.1.174) is an enzyme that catalyzes the chemical reaction

:succinyl-CoA + acetyl-CoA $ightleftharpoons$ CoA + 3-oxoadipyl-CoA

Thus, the two substrates of this enzyme are succinyl-CoA and acetyl-CoA, whereas its two products are CoA and 3-oxoadipyl-CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is succinyl-CoA:acetyl-CoA C-succinyltransferase. This enzyme participates in benzoate degradation via hydroxylation.

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