Ureidoglycolate hydrolase
- Ureidoglycolate hydrolase
In enzymology, an ureidoglycolate hydrolase (EC number|3.5.3.19) is an enzyme that catalyzes the chemical reaction
:(S)-ureidoglycolate + H2O glyoxylate + 2 NH3 + CO2
Thus, the two substrates of this enzyme are (S)-ureidoglycolate and H2O, whereas its 3 products are glyoxylate, NH3, and CO2.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is (S)-ureidoglycolate amidohydrolase (decarboxylating). This enzyme participates in purine metabolism.
tructural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1XSQ, PDB link|1XSR, PDB link|1YQC, and PDB link|2BDR.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|115629-07-7."
Gene Ontology (GO) codes
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