- N-substituted formamide deformylase
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N-substituted formamide deformylase Identifiers EC number 3.5.1.91 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Search PMC articles PubMed articles In enzymology, a N-substituted formamide deformylase (EC 3.5.1.91) is an enzyme that catalyzes the chemical reaction
- N-benzylformamide + H2O formate + benzylamine
Thus, the two substrates of this enzyme are N-benzylformamide and H2O, whereas its two products are formate and benzylamine.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-benzylformamide amidohydrolase. This enzyme is also called NfdA.
References
- Fukatsu H, Hashimoto Y, Goda M, Higashibata H, Kobayashi M (2004). "Amine-synthesizing enzyme N-substituted formamide deformylase: screening, purification, characterization, and gene cloning". Proc. Natl. Acad. Sci. U. S. A. 101 (38): 13726–31. doi:10.1073/pnas.0405082101. PMC 518824. PMID 15358859. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=518824.
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