- N-formylglutamate deformylase
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N-formylglutamate deformylase Identifiers EC number 3.5.1.68 CAS number 97286-12-9 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a N-formylglutamate deformylase (EC 3.5.1.68) is an enzyme that catalyzes the chemical reaction
- N-formyl-L-glutamate + H2O
formate + L-glutamate
Thus, the two substrates of this enzyme are N-formyl-L-glutamate and H2O, whereas its two products are formate and L-glutamate.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-formyl-L-glutamate amidohydrolase. Other names in common use include beta-citryl-L-glutamate hydrolase, formylglutamate deformylase, N-formylglutamate hydrolase, beta-citrylglutamate amidase, beta-citryl-L-glutamate amidohydrolase, beta-citryl-L-glutamate amidase, beta-citrylglutamate amidase, and beta-citryl-L-glutamate-hydrolyzing enzyme. This enzyme participates in histidine metabolism and glyoxylate and dicarboxylate metabolism.
References
- Hu L, Mulfinger LM, Phillips AT (1987). "Purification and properties of formylglutamate amidohydrolase from Pseudomonas putida". J. Bacteriol. 169 (10): 4696–702. PMC 213842. PMID 3308850. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=213842.
- Miyake M, Innami T, Kakimoto Y (1983). "A beta-citryl-L-glutamate-hydrolysing enzyme in rat testes". Biochim. Biophys. Acta. 760 (2): 206–14. PMID 6414521.
This hydrolase article is a stub. You can help Wikipedia by expanding it. - N-formyl-L-glutamate + H2O
