Methenyltetrahydromethanopterin cyclohydrolase

methenyltetrahydromethanopterin cyclohydrolase
Identifiers
EC number	3.5.4.27
CAS number	99533-50-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a methenyltetrahydromethanopterin cyclohydrolase (EC 3.5.4.27) is an enzyme that catalyzes the chemical reaction

5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H₂O $\rightleftharpoons$ 5-formyl-5,6,7,8-tetrahydromethanopterin

Thus, the two substrates of this enzyme are 5,10-methenyl-5,6,7,8-tetrahydromethanopterin and H₂O, whereas its product is 5-formyl-5,6,7,8-tetrahydromethanopterin.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is 5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing). Other names in common use include 5,10-methenyltetrahydromethanopterin cyclohydrolase, N5,N10-methenyltetrahydromethanopterin cyclohydrolase, and methenyl-H4MPT cyclohydrolase. This enzyme participates in folate biosynthesis.

References

• Donnelly MI, Escalante-Semerena JC, Rinehart KL Jr, Wolfe RS (1985). "Methenyl-tetrahydromethanopterin cyclohydrolase in cell extracts of Methanobacterium". Arch. Biochem. Biophys. 242 (2): 430–9. doi:10.1016/0003-9861(85)90227-9. PMID 4062290. 

This hydrolase article is a stub. You can help Wikipedia by expanding it.v · Categories: Hydrolase stubs EC 3.5.4 Enzymes of unknown structure Wikimedia Foundation. 2010. Игры ⚽ Поможем сделать НИР Hole set Leaena Look at other dictionaries: List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia Méthylènetétrahydrométhanoptérine réductase —   N° EC   EC …   Wikipédia en Français 5,10-methylenetetrahydromethanopterin reductase — In enzymology, a 5,10 methylenetetrahydromethanopterin reductase (EC number|1.5.99.11) is an enzyme that catalyzes the chemical reaction:5 methyltetrahydromethanopterin + coenzyme F420 ightleftharpoons 5,10 methylenetetrahydromethanopterin +… …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”