Aryl-acylamidase

aryl-acylamidase
Identifiers
EC number	3.5.1.13
CAS number	9025-18-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, an aryl-acylamidase (EC 3.5.1.13) is an enzyme that catalyzes the chemical reaction

an anilide + H₂O $\rightleftharpoons$ a carboxylate + aniline

Thus, the two substrates of this enzyme are anilide and H₂O, whereas its two products are carboxylate and aniline.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is aryl-acylamide amidohydrolase. Other names in common use include AAA-1, AAA-2, brain acetylcholinesterase (is associated with AAA-2), and pseudocholinesterase (associated with arylacylamidase).

References

• Nimmo-Smith RH (1960). "Aromatic N-deacylation by chick-kidney mitochondria". Biochem. J. 75 (2): 284–293. PMC 1204423. PMID 14427286. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1204423. 

This hydrolase article is a stub. You can help Wikipedia by expanding it.v · Wickedpedia article Wikimedia Foundation. 2010. Игры ⚽ Нужно сделать НИР? Michael Morton (dramatist) Greg Richardson (boxer) Look at other dictionaries: aryl — An organic radical derived from an aromatic compound by removing a hydrogen atom. a. acylamidase an amidohydrolase cleaving the acyl group from an anilide by hydrolysis, producing aniline and an …   Medical dictionary List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français EC 3.5 — Le groupe EC3.5 rassemble des enzymes appartenant à la famille des hydrolases. Elles ont pour particularité de catalyser des réactions d hydrolyse dans des molécules possédant un carbone et un azote liés par liaison simple, double ou triple. À la …   Wikipédia en Français Mite des vêtements —  Pour l’article homonyme, voir Mite.  Mite textile …   Wikipédia en Français arylamidase — SYN: aryl acylamidase …   Medical dictionary 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”