- Arylacetonitrilase
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arylacetonitrilase Identifiers EC number 3.5.5.5 CAS number 132053-06-6 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, an arylacetonitrilase (EC 3.5.5.5) is an enzyme that catalyzes the chemical reaction
- 4-chlorophenylacetonitrile + 2 H2O 4-chlorophenylacetate + NH3
Thus, the two substrates of this enzyme are 4-chlorophenylacetonitrile and H2O, whereas its two products are 4-chlorophenylacetate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. The systematic name of this enzyme class is arylacetonitrile aminohydrolase. This enzyme participates in cyanoamino acid metabolism.
References
- Mauger J, Nagasawa T and Yamada H (1990). "Occurrence of a novel nitrilase, arylacetonitrilase, in Alcaligenes faecalis JM3". Arch. Microbiol. 155: 1–6. doi:10.1007/BF00291265.
- Nagasawa T, Mauger J, Yamada H (1990). "A novel nitrilase, arylacetonitrilase, of Alcaligenes faecalis JM3 Purification and characterization". Eur. J. Biochem. 194 (3): 765–72. doi:10.1111/j.1432-1033.1990.tb19467.x. PMID 2269298.
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