Arginine deiminase

In enzymology, an arginine deiminase (EC number|3.5.3.6) is an enzyme that catalyzes the chemical reaction

:L-arginine + H₂O $ightleftharpoons$ L-citrulline + NH₃

Thus, the two substrates of this enzyme are L-arginine and H₂O, whereas its two products are L-citrulline and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is L-arginine iminohydrolase. Other names in common use include arginine dihydrolase, citrulline iminase, and L-arginine deiminase. This enzyme participates in arginine and proline metabolism.

tructural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1LXY, PDB link|1RXX, PDB link|1S9R, PDB link|2A9G, PDB link|2AAF, PDB link|2ABR, and PDB link|2ACI.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9027-98-9."

Gene Ontology (GO) codes