1-pyrroline-4-hydroxy-2-carboxylate deaminase

In enzymology, a 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC number|3.5.4.22) is an enzyme that catalyzes the chemical reaction

:1-pyrroline-4-hydroxy-2-carboxylate + H₂O $ightleftharpoons$ 2,5-dioxopentanoate + NH₃

Thus, the two substrates of this enzyme are 1-pyrroline-4-hydroxy-2-carboxylate and H₂O, whereas its two products are 2,5-dioxopentanoate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is 1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing). This enzyme is also called HPC deaminase. This enzyme participates in arginine and proline metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9054-77-7."

Gene Ontology (GO) codes