1-aminocyclopropane-1-carboxylate deaminase

In enzymology, a 1-aminocyclopropane-1-carboxylate deaminase (EC number|3.5.99.7) is an enzyme that catalyzes the chemical reaction

:1-aminocyclopropane-1-carboxylate + H₂O $ightleftharpoons$ 2-oxobutanoate + NH₃

Thus, the two substrates of this enzyme are 1-aminocyclopropane-1-carboxylate and H₂O, whereas its two products are 2-oxobutanoate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing). This enzyme is also called 1-aminocyclopropane-1-carboxylate endolyase (deaminating). This enzyme participates in propanoate metabolism. It employs one cofactor, pyridoxal phosphate.

tructural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1RQX, PDB link|1TYZ, PDB link|1TZ2, PDB link|1TZJ, PDB link|1TZK, and PDB link|1TZM.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|69553-48-6."

Gene Ontology (GO) codes