NMN nucleosidase

NMN nucleosidase
Identifiers
EC number	3.2.2.14
CAS number	37237-49-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a NMN nucleosidase (EC 3.2.2.14) is an enzyme that catalyzes the chemical reaction

nicotinamide D-ribonucleotide + H₂O $\rightleftharpoons$ D-ribose 5-phosphate + nicotinamide

Thus, the two substrates of this enzyme are nicotinamide D-ribonucleotide and H₂O, whereas its two products are D-ribose 5-phosphate and nicotinamide.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is nicotinamide-nucleotide phosphoribohydrolase. Other names in common use include NMNase, nicotinamide mononucleotide nucleosidase, nicotinamide mononucleotidase, NMN glycohydrolase, and NMNGhase. This enzyme participates in nicotinate and nicotinamide metabolism.

References

• Andreoli AJ, Okita TW, Bloom R, Grover TA (1972). "The pyridine nucleotide cycle: presence of a nicotinamide mononucleotide-specific glycohydrolase in Escherichia coli". Biochem. Biophys. Res. Commun. 49 (1): 264–9. doi:10.1016/0006-291X(72)90039-3. PMID 4342726. 

This hydrolase article is a stub. You can help Wikipedia by expanding it.v · Categories: Hydrolase stubs EC 3.2.2 Enzymes of unknown structure Wikimedia Foundation. 2010. Игры ⚽ Нужен реферат? Mallein test Salt-effect distillation Look at other dictionaries: List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français EC 3.2 — Le groupe EC3.2[1] est un groupe d enzymes appartenant à la famille des hydrolases, enzymes dont le rôle est de découper des molécules en molécules plus simples. On les nomme glycosylases , parce qu elles coupent les liaisons entre un sucre et le …   Wikipédia en Français 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”