Endoglycosylceramidase

In enzymology, an endoglycosylceramidase (EC number|3.2.1.123) is an enzyme that catalyzes the chemical reaction

:oligoglycosylglucosylceramide + H₂O $ightleftharpoons$ ceramide + oligoglycosylglucose

Thus, the two substrates of this enzyme are oligoglycosylglucosylceramide and H₂O, whereas its two products are ceramide and oligoglycosylglucose.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is oligoglycosylglucosylceramide glycohydrolase. Other names in common use include endoglycoceramidase, EGCase, and glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase.

tructural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2OSW, PDB link|2OSX, PDB link|2OSY, PDB link|2OYK, PDB link|2OYL, and PDB link|2OYM.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|105503-61-5."

Gene Ontology (GO) codes